Literature DB >> 14999511

Vascular endothelial growth factor in colorectal cancer.

Markus Guba1, Hendrik Seeliger, Axel Kleespies, Karl-Walter Jauch, Christiane Bruns.   

Abstract

BACKGROUND: Angiogenesis plays an important role in colorectal cancer progression. Evidence from preclinical and clinical studies indicates that vascular endothelial growth factor (VEGF) is the predominant angiogenic factor in human colorectal cancer and is associated with formation of metastases and poor prognosis. Based on these results it was hypothesized that attacking one or more of the VEGF-mediated mechanisms may be promising in the treatment of colorectal cancer. AIMS. This article reviews the role of VEGF in colon cancer and summarizes recent advances in the treatment of colorectal cancer by anti-VEGF strategies.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14999511     DOI： 10.1007/s00384-003-0576-y

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN： 0179-1958            Impact factor:   2.571


  54 in total

1.  p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts.

Authors:  J Milanini; F Viñals; J Pouysségur; G Pagès
Journal:  J Biol Chem       Date:  1998-07-17       Impact factor: 5.157

2.  Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor.

Authors:  Markus Guba; Philipp von Breitenbuch; Markus Steinbauer; Gudrun Koehl; Stefanie Flegel; Matthias Hornung; Christiane J Bruns; Carl Zuelke; Stefan Farkas; Matthias Anthuber; Karl-Walter Jauch; Edward K Geissler
Journal:  Nat Med       Date:  2002-02       Impact factor: 53.440

3.  Inhibition of liver metastasis of colon cancer by in vivo administration of anti-vascular endothelial growth factor antibody.

Authors:  K Okamoto; Y Oshika; Y Fukushima; M Yoshimura; Y Ohnishi; T Tokunaga; T Hashimoto; H Hatanaka; Y Tomii; Y Yoshida; S Miura; T Tsuchida; H Kijima; H Yamazaki; M Nakamura; Y Ueyama
Journal:  Oncol Rep       Date:  1999 May-Jun       Impact factor: 3.906

4.  NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.

Authors:  O Dormond; A Foletti; C Paroz; C Rüegg
Journal:  Nat Med       Date:  2001-09       Impact factor: 53.440

5.  Soluble vascular endothelial growth factor levels in patients with primary colorectal carcinoma. The Danish RANX05 Colorectal Cancer Study Group.

Authors:  K Werther; I J Christensen; N Brünner; H J Nielsen
Journal:  Eur J Surg Oncol       Date:  2000-11       Impact factor: 4.424

6.  Enhancement of angiogenesis, tumor growth, and metastasis by transfection of vascular endothelial growth factor into LoVo human colon cancer cell line.

Authors:  Y Kondo; S Arii; A Mori; M Furutani; T Chiba; M Imamura
Journal:  Clin Cancer Res       Date:  2000-02       Impact factor: 12.531

7.  Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cells.

Authors:  Y D Jung; K Nakano; W Liu; G E Gallick; L M Ellis
Journal:  Cancer Res       Date:  1999-10-01       Impact factor: 12.701

8.  Prognostic role of serum vascular endothelial growth factor, basic fibroblast growth factor and nitric oxide in patients with colorectal carcinoma.

Authors:  Hakan Akbulut; Fevzi Altuntas; K Gonca Akbulut; Guler Ozturk; Mehmet Cindoruk; Ekrem Unal; Fikri Icli
Journal:  Cytokine       Date:  2002-11-24       Impact factor: 3.861

Review 9.  Angiogenesis in cancer, vascular, rheumatoid and other disease.

Authors:  J Folkman
Journal:  Nat Med       Date:  1995-01       Impact factor: 53.440

Review 10.  Targeting vascular endothelial growth factor in colorectal cancer.

Authors:  Jordan D Berlin
Journal:  Oncology (Williston Park)       Date:  2002-08       Impact factor: 2.990
View more
  23 in total

Review 1.  Targeting the vasculature of visceral tumors: novel insights and treatment perspectives.

Authors:  L V Klotz; M E Eichhorn; B Schwarz; H Seeliger; M K Angele; K-W Jauch; Christiane J Bruns
Journal:  Langenbecks Arch Surg       Date:  2012-03-14       Impact factor: 3.445

2.  Expression profile of NF-κB regulated genes in sporadic colorectal cancer patients.

Authors:  Betsy Annel González-Quezada; Uriel Francisco Santana-Bejarano; Alfredo Corona-Rivera; Helia Judith Pimentel-Gutiérrez; Rocío Silva-Cruz; Citlalli Ortega-De-la-Torre; Ramón Franco-Topete; Karina Franco-Topete; Manuel Willebaldo Centeno-Flores; Víctor Manuel Maciel-Gutiérrez; Jorge Román Corona-Rivera; Juan Armendáriz-Borunda; Lucina Bobadilla-Morales
Journal:  Oncol Lett       Date:  2018-03-07       Impact factor: 2.967

Review 3.  Comprehensive review of targeted therapy for colorectal cancer.

Authors:  Yuan-Hong Xie; Ying-Xuan Chen; Jing-Yuan Fang
Journal:  Signal Transduct Target Ther       Date:  2020-03-20

4.  Phospho-STAT5 expression is associated with poor prognosis of human colonic adenocarcinoma.

Authors:  Yin-Ling Mao; Zhi-Wei Li; Chang-Jie Lou; Da Pang; Yan-Qiao Zhang
Journal:  Pathol Oncol Res       Date:  2011-01-14       Impact factor: 3.201

5.  Selective inhibition of endothelin receptor A as an anti-angiogenic and anti-proliferative strategy for human pancreatic cancer.

Authors:  Sarah Bhargava; Till Stummeyer; Birgit Hotz; O Joe Hines; Howard A Reber; Heinz J Buhr; Hubert G Hotz
Journal:  J Gastrointest Surg       Date:  2005 May-Jun       Impact factor: 3.452

6.  Vascular endothelial growth factor polymorphisms and lung cancer risk.

Authors:  Junli Fan; Weiguo Zhang; Caipeng Lei; Bin Qiao; Qin Liu; Qiang Chen; Hongduo Jiao; Leizhen Jiang; Shuo Cui; Jianmin Chen
Journal:  Int J Clin Exp Med       Date:  2015-04-15

7.  Selecting Potential Targetable Biomarkers for Imaging Purposes in Colorectal Cancer Using TArget Selection Criteria (TASC): A Novel Target Identification Tool.

Authors:  Marleen van Oosten; Lucia Ma Crane; Joost Bart; Fijs W van Leeuwen; Gooitzen M van Dam
Journal:  Transl Oncol       Date:  2011-04-01       Impact factor: 4.243

Review 8.  Following up tumour angiogenesis: from the basic laboratory to the clinic.

Authors:  José L Orgaz; Beatriz Martínez-Poveda; Nuria I Fernández-García; Benilde Jiménez
Journal:  Clin Transl Oncol       Date:  2008-08       Impact factor: 3.405

9.  A gastrin precursor, gastrin-gly, upregulates VEGF expression in colonic epithelial cells through an HIF-1-independent mechanism.

Authors:  Claudine Bertrand; Aline Kowalski-Chauvel; Catherine Do; Cécile Résa; Souad Najib; Laurence Daulhac; Timothy C Wang; Audrey Ferrand; Catherine Seva
Journal:  Int J Cancer       Date:  2010-06-15       Impact factor: 7.396

10.  Association between EGF, TGF-beta1, VEGF gene polymorphism and colorectal cancer.

Authors:  Guo-yang Wu; Till Hasenberg; Richard Magdeburg; Roderich Bönninghoff; Jörg W Sturm; Michael Keese
Journal:  World J Surg       Date:  2009-01       Impact factor: 3.352
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.