BACKGROUND: Mammograms are assigned a BI-RADS (Breast Imaging Reporting and Data System) category, which indicates the level of suspicion for cancer. OBJECTIVES: (i) To evaluate the use of BI-RADS categories in a non-academic radiology practice based in a community hospital compared with local radiology private offices; (ii) to determine positive predictive value (PPV), sensitivity and specificity of mammograms; and (iii) to explore the correlation of BI-RAD 3-5 and lesion description with diagnosis of cancer. PATIENTS AND METHODS: We performed 947 SVABBs (stereotactic vacuum-assisted breast biopsies) on 911 patients with BI-RADS 3-5. Lesions were classified as: 1=microcalcifications; 2=asymmetric density; 3=circumscribed mass; and 4=spiculated mass. RESULTS: BI-RADS category correlated with diagnosis of breast cancer (atypia excluded): category 3=4%; category 4=15%; and category 5=79%. The PPV of BI-RADS 4 and 5 for breast cancer or atypia was 20%, in contrast to 5% for BI-RADS 3. Sensitivity and specificity were 95% and 19%, respectively. For BI-RADS 3 without microcalcifications only 3% were positive, in contrast to 8% for remainder. CONCLUSIONS: First, there is a stepwise increase in cancer for each of the BI-RADS categories 3-5. Secondly, in BI-RADS 3 with microcalcifications, a biopsy is indicated according to our findings. Finally, the sensitivity of mammograms is 95% but the specificity is 19%.
BACKGROUND: Mammograms are assigned a BI-RADS (Breast Imaging Reporting and Data System) category, which indicates the level of suspicion for cancer. OBJECTIVES: (i) To evaluate the use of BI-RADS categories in a non-academic radiology practice based in a community hospital compared with local radiology private offices; (ii) to determine positive predictive value (PPV), sensitivity and specificity of mammograms; and (iii) to explore the correlation of BI-RAD 3-5 and lesion description with diagnosis of cancer. PATIENTS AND METHODS: We performed 947 SVABBs (stereotactic vacuum-assisted breast biopsies) on 911 patients with BI-RADS 3-5. Lesions were classified as: 1=microcalcifications; 2=asymmetric density; 3=circumscribed mass; and 4=spiculated mass. RESULTS: BI-RADS category correlated with diagnosis of breast cancer (atypia excluded): category 3=4%; category 4=15%; and category 5=79%. The PPV of BI-RADS 4 and 5 for breast cancer or atypia was 20%, in contrast to 5% for BI-RADS 3. Sensitivity and specificity were 95% and 19%, respectively. For BI-RADS 3 without microcalcifications only 3% were positive, in contrast to 8% for remainder. CONCLUSIONS: First, there is a stepwise increase in cancer for each of the BI-RADS categories 3-5. Secondly, in BI-RADS 3 with microcalcifications, a biopsy is indicated according to our findings. Finally, the sensitivity of mammograms is 95% but the specificity is 19%.
Authors: Ronilda Lacson; Kimberly Harris; Phyllis Brawarsky; Tor D Tosteson; Tracy Onega; Anna N A Tosteson; Abby Kaye; Irina Gonzalez; Robyn Birdwell; Jennifer S Haas Journal: J Digit Imaging Date: 2015-10 Impact factor: 4.056
Authors: Yirong Wu; Oguzhan Alagoz; Mehmet U S Ayvaci; Alejandro Munoz Del Rio; David J Vanness; Ryan Woods; Elizabeth S Burnside Journal: J Digit Imaging Date: 2013-10 Impact factor: 4.056
Authors: A-S Hamy; S Giacchetti; M Albiter; C de Bazelaire; C Cuvier; F Perret; S Bonfils; P Charvériat; H Hocini; A de Roquancourt; M Espie Journal: Eur Radiol Date: 2011-07-16 Impact factor: 5.315
Authors: Janet K Baum; Lucy G Hanna; Suddhasatta Acharyya; Mary C Mahoney; Emily F Conant; Lawrence W Bassett; Etta D Pisano Journal: Radiology Date: 2011-04-18 Impact factor: 11.105
Authors: Anna Linda; Chiara Zuiani; Viviana Londero; Eleonora Di Gaetano; Anna Dal Col; Rossano Girometti; Massimo Bazzocchi Journal: Radiol Med Date: 2013-12-03 Impact factor: 3.469
Authors: George C Zografos; Flora Zagouri; Theodoros N Sergentanis; Dimitra Koulocheri; Afroditi Nonni; Vassiliki Oikonomou; Philip Domeyer; Maria Kotsani; Constantine Fotiadis; John Bramis Journal: World J Surg Oncol Date: 2007-05-14 Impact factor: 2.754