Literature DB >> 14990455

FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes.

Fátima Al-Shahrour1, Ramón Díaz-Uriarte, Joaquín Dopazo.   

Abstract

We present a simple but powerful procedure to extract Gene Ontology (GO) terms that are significantly over- or under-represented in sets of genes within the context of a genome-scale experiment (DNA microarray, proteomics, etc.). Said procedure has been implemented as a web application, FatiGO, allowing for easy and interactive querying. FatiGO, which takes the multiple-testing nature of statistical contrast into account, currently includes GO associations for diverse organisms (human, mouse, fly, worm and yeast) and the TrEMBL/Swissprot GOAnnotations@EBI correspondences from the European Bioinformatics Institute.

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Year:  2004        PMID: 14990455     DOI: 10.1093/bioinformatics/btg455

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  433 in total

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