| Literature DB >> 14986953 |
Craig A Miller1, Robert A Batey.
Abstract
Hetero Diels-Alder reactions of transient nitrosoamidines are reported. Transient nitrosoamidines are formed by oxidation of protected N-hydroxylguanidines and are trapped in situ by 1,3-dienes to give [4 + 2] cycloadducts in good yields and regioselectivity. The resultant cycloadducts are versatile intermediates for the formation of functionalized guanidines. [reaction: see text]Entities:
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Year: 2004 PMID： 14986953 DOI： 10.1021/ol0363117
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005