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Literature DB >> 14984251

Pharmaceutical prospects for RNA interference.

Raymond M Schiffelers¹, Martin C Woodle, Puthupparampil Scaria.

Abstract

RNA interference has proven to be a powerful tool in gene function validation. Recently, the first studies were published reporting a disease-modulating activity of the technique, suggesting a promise for RNA interference as a novel therapeutic strategy. This review discusses the recent advancements in realizing the clinical utility of RNA-interference.

Mesh：

Substances：
RNA, Small Interfering

Year: 2004 PMID： 14984251 DOI： 10.1023/b:pham.0000012145.49054.6c

Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200

50 in total

Review 1. Post-transcriptional gene silencing across kingdoms.

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Journal: Curr Opin Genet Dev Date: 2000-12 Impact factor: 5.578

2. Localized expression of small RNA inhibitors in human cells.

Authors: Cynthia P Paul; Paul D Good; Shirley X L Li; Annette Kleihauer; John J Rossi; David R Engelke
Journal: Mol Ther Date: 2003-02 Impact factor: 11.454

Review 3. In vivo characteristics of cationic liposomes as delivery vectors for gene therapy.

Authors: Sandrine A L Audouy; Lou F M H de Leij; Dick Hoekstra; Grietje Molema
Journal: Pharm Res Date: 2002-11 Impact factor: 4.200

Review 4. Small interfering RNAs and their chemical synthesis.

Authors: Ronald Micura
Journal: Angew Chem Int Ed Engl Date: 2002-07-02 Impact factor: 15.336

Review 5. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer.

Authors: Thomas Merdan; Jindrich Kopecek; Thomas Kissel
Journal: Adv Drug Deliv Rev Date: 2002-09-13 Impact factor: 15.470

6. Breakthrough of the year. Small RNAs make big splash.

Authors: Jennifer Couzin
Journal: Science Date: 2002-12-20 Impact factor: 47.728

7. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans.

Authors: A Fire; S Xu; M K Montgomery; S A Kostas; S E Driver; C C Mello
Journal: Nature Date: 1998-02-19 Impact factor: 49.962

8. Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor.

Authors: Torgeir Holen; Mohammed Amarzguioui; Merete T Wiiger; Eshrat Babaie; Hans Prydz
Journal: Nucleic Acids Res Date: 2002-04-15 Impact factor: 16.971

9. siRNA-mediated gene silencing in vitro and in vivo.

Authors: Haibin Xia; Qinwen Mao; Henry L Paulson; Beverly L Davidson
Journal: Nat Biotechnol Date: 2002-09-16 Impact factor: 54.908

10. Analysis of gene function in somatic mammalian cells using small interfering RNAs.

Authors: Sayda M Elbashir; Jens Harborth; Klaus Weber; Thomas Tuschl
Journal: Methods Date: 2002-02 Impact factor: 3.608

17 in total

1. Sticky wickets in lower nephron nephrosis.

Authors: Friedrich C Luft
Journal: J Physiol Date: 2004-04-08 Impact factor: 5.182

Review 2. Gene modulation for treating liver fibrosis.

Authors: Kun Cheng; Ram I Mahato
Journal: Crit Rev Ther Drug Carrier Syst Date: 2007 Impact factor: 4.889

Review 3. Nanoparticles for nucleic acid delivery: Applications in cancer immunotherapy.

Authors: Alvin J Mukalel; Rachel S Riley; Rui Zhang; Michael J Mitchell
Journal: Cancer Lett Date: 2019-05-14 Impact factor: 8.679

4. Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles.

Authors: Mian M K Shahzad; Lingegowda S Mangala; Hee Dong Han; Chunhua Lu; Justin Bottsford-Miller; Masato Nishimura; Edna M Mora; Jeong-Won Lee; Rebecca L Stone; Chad V Pecot; Duangmani Thanapprapasr; Ju-Won Roh; Puja Gaur; Maya P Nair; Yun-Yong Park; Nirupama Sabnis; Michael T Deavers; Ju-Seog Lee; Lee M Ellis; Gabriel Lopez-Berestein; Walter J McConathy; Laszlo Prokai; Andras G Lacko; Anil K Sood
Journal: Neoplasia Date: 2011-04 Impact factor: 5.715

5. Multifunctional Poly(amine-co-ester-co-ortho ester) for Efficient and Safe Gene Delivery.

Authors: Junwei Zhang; Jiajia Cui; Yang Deng; Zhaozhong Jiang; W Mark Saltzman
Journal: ACS Biomater Sci Eng Date: 2016-09-26

6. Very long chain N4, N9 -diacyl spermines: non-viral lipopolyamine vectors for efficient plasmid DNA and siRNA delivery.

Authors: Hassan M Ghonaim; Shi Li; Ian S Blagbrough
Journal: Pharm Res Date: 2008-09-10 Impact factor: 4.200

7. N1,N12-Diacyl spermines: SAR studies on non-viral lipopolyamine vectors for plasmid DNA and siRNA formulation.

Authors: Hassan M Ghonaim; Shi Li; Ian S Blagbrough
Journal: Pharm Res Date: 2009-10-30 Impact factor: 4.200

8. Animal Models in Behçet's Disease.

Authors: Ozlem Yildirim
Journal: Patholog Res Int Date: 2012-02-27

9. Disulfide-based poly(amido amine)s for siRNA delivery: effects of structure on siRNA complexation, cellular uptake, gene silencing and toxicity.

Authors: Pieter Vader; Leonardus J van der Aa; Johan F J Engbersen; Gert Storm; Raymond M Schiffelers
Journal: Pharm Res Date: 2010-12-23 Impact factor: 4.200

10. Cationic nano-copolymers mediated IKKbeta targeting siRNA inhibit the proliferation of human Tenon's capsule fibroblasts in vitro.

Authors: Yongheng Duan; Xipeng Guan; Jian Ge; Daping Quan; Yehong Zhuo; Hehua Ye; Tingting Shao
Journal: Mol Vis Date: 2008-12-31 Impact factor: 2.367