Literature DB >> 14980595

Solid phase synthesis of selective caspase-3 peptide inhibitors.

Erich L Grimm1, Bruno Roy, Renee Aspiotis, Christopher I Bayly, Donald W Nicholson, Dita M Rasper, Johanne Renaud, Sophie Roy, John Tam, Paul Tawa, John P Vaillancourt, Steven Xanthoudakis, Robert J Zamboni.   

Abstract

A robust method for the solid phase synthesis of a series of selective caspase-3 peptide inhibitors is described. The inhibitors can be obtained after cleavage from the solid support without further purification.

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Year:  2004        PMID: 14980595     DOI: 10.1016/j.bmc.2004.01.007

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  3 in total

Review 1.  Small Molecule Active Site Directed Tools for Studying Human Caspases.

Authors:  Marcin Poreba; Aleksandra Szalek; Paulina Kasperkiewicz; Wioletta Rut; Guy S Salvesen; Marcin Drag
Journal:  Chem Rev       Date:  2015-11-09       Impact factor: 60.622

2.  Evaluating the effect of ionic strength on duplex stability for PNA having negatively or positively charged side chains.

Authors:  N Tilani S De Costa; Jennifer M Heemstra
Journal:  PLoS One       Date:  2013-03-06       Impact factor: 3.240

3.  Pharmacophore modeling and docking studies on some nonpeptide-based caspase-3 inhibitors.

Authors:  Simant Sharma; Arijit Basu; R K Agrawal
Journal:  Biomed Res Int       Date:  2013-09-08       Impact factor: 3.411

  3 in total

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