Literature DB >> 14980340

Seizure secondary to citalopram overdose.

Peter John Cuenca1, Kurtis Rex Holt, Jeffrey David Hoefle.   

Abstract

Selective serotonin reuptake inhibitors (SSRIs) are widely used in the community for treating many forms of mental illness. Citalopram, a newer generation SSRI, is commonly prescribed but, despite its low toxicity profile, has a danger of seizure and dysrhythmias in overdose. This case report documents the key aspects in treatment of a citalopram overdose resulting in a seizure and an episode of supraventricular tachycardia (SVT). The seizure was successfully treated with benzodiazepines. The SVT was terminated with administration of adenosine. We review the literature and make recommendations on treatment of citalopram overdose.

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Year:  2004        PMID: 14980340     DOI: 10.1016/j.jemermed.2003.06.005

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  6 in total

1.  Citalopram Overdose: a Fatal Case.

Authors:  Erik P Kraai; Steven A Seifert
Journal:  J Med Toxicol       Date:  2015-06

2.  Predictive factors for generalized seizures after deliberate citalopram overdose.

Authors:  W Stephen Waring; Julie A Gray; Ann Graham
Journal:  Br J Clin Pharmacol       Date:  2008-12       Impact factor: 4.335

3.  Distinct Epileptogenic Mechanisms Associated with Seizures in Wolf-Hirschhorn Syndrome.

Authors:  Thiago Corrêa; Maytza Mayndra; Cíntia B Santos-Rebouças
Journal:  Mol Neurobiol       Date:  2022-03-12       Impact factor: 5.590

4.  Massive Citalopram Overdose Associated with Recurrent Seizures and Bilateral Shoulder Dislocations.

Authors:  Shafeajafar Zoofaghari; Anselm Wong; Pegah Kiarasi; Farzad Gheshlaghi
Journal:  J Res Pharm Pract       Date:  2020-10-08

5.  Prediction of Ventricular Arrhythmias by QRS/QTc - Ratio in Citalopram or Escitalopram Intoxication.

Authors:  Erik Sveberg Dietrichs; Godfrey L Smith
Journal:  Front Med (Lausanne)       Date:  2022-03-16

6.  Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database.

Authors:  Trevor Hill; Carol Coupland; Richard Morriss; Antony Arthur; Michael Moore; Julia Hippisley-Cox
Journal:  BMC Psychiatry       Date:  2015-12-17       Impact factor: 3.630

  6 in total

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