Literature DB >> 14977989

Inhibitory effect of antiserum to surface antigen P50 of Babesia gibsoni on growth of parasites in severe combined immunodeficiency mice given canine red blood cells.

Shinya Fukumoto1, Xuenan Xuan, Noriyuki Takabatake, Ikuo Igarashi, Chihiro Sugimoto, Kozo Fujisaki, Hideyuki Nagasawa, Takeshi Mikami, Hiroshi Suzuki.   

Abstract

The inhibitory effect of an antiserum to surface protein P50 of Babesia gibsoni on the growth of the parasite was determined with severe combined immunodeficiency mice given canine red blood cells. The antiserum to the recombinant P50 protein significantly inhibited the parasite growth, indicating that P50 might be a useful vaccine candidate.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14977989      PMCID： PMC356003          DOI： 10.1128/IAI.72.3.1795-1798.2004

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  16 in total

1.  Fatal Babesia gibsoni infection in a dog from Spain.

Authors:  M L Suarez; L Espino; A Goicoa; L E Fidalgo; G Santamarina
Journal:  Vet Rec       Date:  2001-06-30       Impact factor: 2.695

2.  Babesia gibsoni infection among dogs in the southeastern United States.

Authors:  Douglass K Macintire; Mary K Boudreaux; Gretchen D West; Candace Bourne; James C Wright; Patricia A Conrad
Journal:  J Am Vet Med Assoc       Date:  2002-02-01       Impact factor: 1.936

3.  Canine piroplasmosis due to Babesia gibsoni: clinical and morphological aspects.

Authors:  R Casapulla; L Baldi; V Avallone; R Sannino; L Pazzanese; V Mizzoni
Journal:  Vet Rec       Date:  1998-02-14       Impact factor: 2.695

4.  Isolation of Plasmodium berghei (malaria) parasites by ammonium chloride lysis of infected erythrocytes.

Authors:  W J Martin; J Finerty; A Rosenthal
Journal:  Nat New Biol       Date:  1971-10-27

5.  Immunosuppression in dogs naturally infected with Babesia gibsoni.

Authors:  K Adachi; C Ueno; S Makimura
Journal:  J Vet Med Sci       Date:  1993-06       Impact factor: 1.267

6.  Vaccination of dogs against Babesia canis infection using parasite antigens from in vitro culture.

Authors:  T P Schetters; J Kleuskens; N Scholtes; H J Bos
Journal:  Parasite Immunol       Date:  1992-05       Impact factor: 2.280

7.  Morphological changes of Babesia gibsoni grown in canine red blood cell-substituted severe combined immune deficiency mice.

Authors:  S Fukumoto; X Xuan; I Igarashi; S Zhang; J Mugisha; T Ogata; H Nagasawa; K Fujisaki; N Suzuki; T Mikami
Journal:  J Parasitol       Date:  2000-10       Impact factor: 1.276

8.  Clinical observations on Babesia gibsoni and Babesia canis infections in dogs.

Authors:  G E Farwell; E K LeGrand; C C Cobb
Journal:  J Am Vet Med Assoc       Date:  1982-03-01       Impact factor: 1.936

9.  High-level expression of truncated surface antigen P50 of Babesia gibsoni in insect cells by baculovirus and evaluation of its immunogenicity and antigenicity.

Authors:  Shinya Fukumoto; Xuenan Xuan; Kimie Kadota; Ikuo Igarashi; Chihiro Sugimoto; Kozo Fujisaki; Hideyuki Nagasawa; Takeshi Mikami; Hiroshi Suzuki
Journal:  Clin Diagn Lab Immunol       Date:  2003-07

10.  Continuous in vitro culture of erythrocytic stages of Babesia gibsoni and virulence of the cultivated parasite.

Authors:  Fujiko Sunaga; Kazuhiko Namikawa; Yasunori Kanno
Journal:  J Vet Med Sci       Date:  2002-07       Impact factor: 1.267
View more
  3 in total

1.  Immunization with recombinant surface antigen P50 of Babesia gibsoni expressed in insect cells induced parasite growth inhibition in dogs.

Authors:  Shinya Fukumoto; Yoh Tamaki; Hiroaki Shirafuji; Shinji Harakawa; Hiroshi Suzuki; Xuenan Xuan
Journal:  Clin Diagn Lab Immunol       Date:  2005-04

2.  Structural and functional characterization of Bc28.1, major erythrocyte-binding protein from Babesia canis merozoite surface.

Authors:  Yin-Shan Yang; Brice Murciano; Karina Moubri; Prisca Cibrelus; Theo Schetters; André Gorenflot; Stéphane Delbecq; Christian Roumestand
Journal:  J Biol Chem       Date:  2012-01-31       Impact factor: 5.157

Review 3.  New Molecules in Babesia gibsoni and their application for diagnosis, vaccine development, and drug discovery.

Authors:  Youn-Kyoung Goo; Xuenan Xuan
Journal:  Korean J Parasitol       Date:  2014-08-29       Impact factor: 1.341
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.