OBJECTIVE: To determine if interferential current (IFC) or transcutaneous electric nerve stimulation (TENS) alters C and A delta fiber-mediated thermal perception thresholds. DESIGN: Single-blind, randomized controlled trial. SETTING: Laboratory. PARTICIPANTS: One hundred forty healthy women volunteers (mean age +/- standard deviation, 20.6+/-2.7 y). INTERVENTIONS: Subjects were randomly and exclusively assigned to 1 of 7 groups (n=20 in each): 0, 5, and 100 Hz of IFC; 5 and 100 Hz of TENS; placebo and control stimulation. Stimulation was applied through 2 electrodes placed over the median nerve. Warm sensation, cold sensation, hot pain, and cold pain perception thresholds were measured from the thenar eminence by using a quantitative sensory testing device and a method of limits algorithm. MAIN OUTCOME MEASURES: Warm sensation, cold sensation, hot pain, and cold pain thresholds (degrees C) before, during, and after stimulation. RESULTS: There was a statistically significant effect of time for all 4 thermal perception thresholds (separate 2-way analyses of variance with repeated measures, all P<.001). There were no statistically significant differences between experimental groups, nor any interaction effects (all P>.05). CONCLUSIONS: Neither IFC nor TENS altered C and A delta fiber-mediated thermal perception thresholds. The results suggest that any analgesic mechanisms with these modalities are likely to be complex.
RCT Entities:
OBJECTIVE: To determine if interferential current (IFC) or transcutaneous electric nerve stimulation (TENS) alters C and A delta fiber-mediated thermal perception thresholds. DESIGN: Single-blind, randomized controlled trial. SETTING: Laboratory. PARTICIPANTS: One hundred forty healthy women volunteers (mean age +/- standard deviation, 20.6+/-2.7 y). INTERVENTIONS: Subjects were randomly and exclusively assigned to 1 of 7 groups (n=20 in each): 0, 5, and 100 Hz of IFC; 5 and 100 Hz of TENS; placebo and control stimulation. Stimulation was applied through 2 electrodes placed over the median nerve. Warm sensation, cold sensation, hot pain, and cold pain perception thresholds were measured from the thenar eminence by using a quantitative sensory testing device and a method of limits algorithm. MAIN OUTCOME MEASURES: Warm sensation, cold sensation, hot pain, and cold pain thresholds (degrees C) before, during, and after stimulation. RESULTS: There was a statistically significant effect of time for all 4 thermal perception thresholds (separate 2-way analyses of variance with repeated measures, all P<.001). There were no statistically significant differences between experimental groups, nor any interaction effects (all P>.05). CONCLUSIONS: Neither IFC nor TENS altered C and A delta fiber-mediated thermal perception thresholds. The results suggest that any analgesic mechanisms with these modalities are likely to be complex.
Authors: R E Liebano; C G Vance; B A Rakel; J E Lee; N A Cooper; S Marchand; D M Walsh; K A Sluka Journal: Eur J Pain Date: 2013-05-06 Impact factor: 3.931
Authors: Barbara Rakel; Nicholas Cooper; Heather J Adams; Bryan R Messer; Laura A Frey Law; Douglas R Dannen; Carrie A Miller; Anya C Polehna; Rachelle C Ruggle; Carol G T Vance; Deirdre M Walsh; Kathleen A Sluka Journal: J Pain Date: 2009-11-27 Impact factor: 5.820
Authors: C Ramesh; Sharad S Sawant; Deepak R Kolte; Barun Kumar; Kosuru Kranthi; Tejal R Patil; J Suresh Babu; C Swarnalatha; Abhishek Singh Nayyar Journal: Asian J Neurosurg Date: 2021-09-07