Literature DB >> 1497018

The stigma of disease: implications of genetic screening.

H Markel1.   

Abstract

As the field of human genetics successfully continues to unravel the secrets of an individual's genetic makeup, the social processes of stigmatization and ostracism of those with "undesirable" traits have the potential to increase. An historical example that may shed light on the problems of applying genetic technology to disease prevention is the institution of quarantine. This essay discusses the concept of "quarantine mentality" and the desire for healthy society to separate itself from those labeled "ill" or abnormal, and addresses two episodes in American history when genetics was applied to the formulation of social policy toward the "diseased": the eugenics movement of the early 20th century and the early attempts of genetic screening programs for sickle cell anemia during the 1970s.

Entities:  

Keywords:  Eugenics Record Office; Genetics and Reproduction; Twentieth Century

Mesh:

Year:  1992        PMID: 1497018     DOI: 10.1016/0002-9343(92)90052-d

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  30 in total

1.  The Human Genome Project: A Public Forum -- Report on a model conference for genetics professionals and consumers.

Authors:  Deborah L Eunpu; Joan O Weiss
Journal:  J Genet Couns       Date:  1993-06       Impact factor: 2.537

2.  Improving communication between doctors and parents after newborn screening.

Authors:  Michael H Farrell; Stephanie A Christopher; Audrey Tluczek; Karen Kennedy-Parker; Alison La Pean; Kerry Eskra; Jenelle Collins; Gary Hoffman; Julie Panepinto; Philip M Farrell
Journal:  WMJ       Date:  2011-10

3.  Using qualitative and quantitative strategies to evaluate knowledge and perceptions about sickle cell disease and sickle cell trait.

Authors:  Marsha J Treadwell; Lakenya McClough; Elliott Vichinsky
Journal:  J Natl Med Assoc       Date:  2006-05       Impact factor: 1.798

4.  Sickle cell screening policies as portent: how will the human genome project affect public sector genetic services?

Authors:  D D Phoenix; S M Lybrook; R W Trottier; F C Hodgin; L A Crandall
Journal:  J Natl Med Assoc       Date:  1995-11       Impact factor: 1.798

5.  Development and validation of an instrument to measure the impact of genetic testing on self-concept in Lynch syndrome.

Authors:  M J Esplen; N Stuckless; S Gallinger; M Aronson; H Rothenmund; K Semotiuk; J Stokes; C Way; J Green; K Butler; H V Petersen; J Wong
Journal:  Clin Genet       Date:  2011-10-03       Impact factor: 4.438

6.  Community engagement about genetic variation research.

Authors:  Sharon F Terry; Kurt D Christensen; Susan Metosky; Gayle Rudofsky; Kathleen P Deignan; Hulda Martinez; Penelope Johnson-Moore; Toby Citrin
Journal:  Popul Health Manag       Date:  2011-08-04       Impact factor: 2.459

Review 7.  Neonatal screening for sickle cell disorders: what about the carrier infants?

Authors:  L Laird; C Dezateux; E N Anionwu
Journal:  BMJ       Date:  1996-08-17

8.  Advantages of expanded universal carrier screening: what is at stake?

Authors:  Sanne van der Hout; Kim Ca Holtkamp; Lidewij Henneman; Guido de Wert; Wybo J Dondorp
Journal:  Eur J Hum Genet       Date:  2016-09-28       Impact factor: 4.246

Review 9.  Human genome research and the public interest: progress notes from an American science policy experiment.

Authors:  E T Juengst
Journal:  Am J Hum Genet       Date:  1994-01       Impact factor: 11.025

10.  The FAP self-concept scale (adult form).

Authors:  Mary Jane Esplen; Noreen Stuckless; Terri Berk; Kate Butler; Steve Gallinger
Journal:  Fam Cancer       Date:  2008-08-13       Impact factor: 2.375

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