Literature DB >> 14963171

Role of indoleamine-2,3-dioxygenase in alpha/beta and gamma interferon-mediated antiviral effects against herpes simplex virus infections.

O Adams1, K Besken, C Oberdörfer, C R MacKenzie, O Takikawa, W Däubener.   

Abstract

Gamma interferon (IFN-gamma)-mediated indoleamine-2,3-dioxygenase (IDO) activity in human astrocytoma cells and in native astrocytes was found to be responsible for the inhibition of herpes simplex virus replication. The effect is abolished in the presence of excess amounts of L-tryptophan. Both IFN-alpha and IFN-beta restricted herpes simplex virus replication in both cell types, but (in contrast to the results seen with IFN-gamma) the addition of an excess amount of L-tryptophan did not inhibit the induced antiviral effect.

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Year:  2004        PMID： 14963171      PMCID： PMC369218          DOI： 10.1128/jvi.78.5.2632-2636.2004

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  44 in total

1.  Restriction of Toxoplasma gondii growth in human brain microvascular endothelial cells by activation of indoleamine 2,3-dioxygenase.

Authors:  W Däubener; B Spors; C Hucke; R Adam; M Stins; K S Kim; H Schroten
Journal:  Infect Immun       Date:  2001-10       Impact factor: 3.441

2.  Establishment of latent herpes simplex virus type 1 infection in resistant, sensitive, and immunodeficient mouse strains.

Authors:  A R Ellison; L Yang; C Voytek; T P Margolis
Journal:  Virology       Date:  2000-03-01       Impact factor: 3.616

Review 3.  The expanding spectrum of herpesvirus infections of the nervous system.

Authors:  B K Kleinschmidt-DeMasters; D H Gilden
Journal:  Brain Pathol       Date:  2001-10       Impact factor: 6.508

Review 4.  Herpes simplex virus infections.

Authors:  R J Whitley; B Roizman
Journal:  Lancet       Date:  2001-05-12       Impact factor: 79.321

5.  Activation of cellular interferon-responsive genes after infection of human cells with herpes simplex virus type 1.

Authors:  Mary Jane Nicholl; Laurence H Robinson; Chris M Preston
Journal:  J Gen Virol       Date:  2000-09       Impact factor: 3.891

6.  Potential role of human brain microvascular endothelial cells in the pathogenesis of brain abscess: inhibition of Staphylococcus aureus by activation of indoleamine 2,3-dioxygenase.

Authors:  H Schroten; B Spors; C Hucke; M Stins; K S Kim; R Adam; W Däubener
Journal:  Neuropediatrics       Date:  2001-08       Impact factor: 1.947

7.  Presence of herpes simplex virus (HSV) in peripheral leukocytes of patient who developed active HSV infection after bone marrow transplantation.

Authors:  K Roubalová; A Suchánková; A Vítek; J Sajdová
Journal:  J Clin Virol       Date:  2000-06       Impact factor: 3.168

8.  Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation.

Authors:  P Hwu; M X Du; R Lapointe; M Do; M W Taylor; H A Young
Journal:  J Immunol       Date:  2000-04-01       Impact factor: 5.422

9.  Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan.

Authors:  E R Pfefferkorn
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

10.  Nitric oxide inhibits hepatitis B virus replication in the livers of transgenic mice.

Authors:  L G Guidotti; H McClary; J M Loudis; F V Chisari
Journal:  J Exp Med       Date:  2000-04-03       Impact factor: 14.307
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  50 in total

Review 1.  Evolution to a chronic disease niche correlates with increased sensitivity to tryptophan availability for the obligate intracellular bacterium Chlamydia pneumoniae.

Authors:  Wilhelmina M Huston; Christopher J Barker; Anu Chacko; Peter Timms
Journal:  J Bacteriol       Date:  2014-03-28       Impact factor: 3.490

2.  Protein Malnutrition Alters Tryptophan and Angiotensin-Converting Enzyme 2 Homeostasis and Adaptive Immune Responses in Human Rotavirus-Infected Gnotobiotic Pigs with Human Infant Fecal Microbiota Transplant.

Authors:  David D Fischer; Sukumar Kandasamy; Francine C Paim; Stephanie N Langel; Moyasar A Alhamo; Lulu Shao; Juliet Chepngeno; Ayako Miyazaki; Huang-Chi Huang; Anand Kumar; Gireesh Rajashekara; Linda J Saif; Anastasia N Vlasova
Journal:  Clin Vaccine Immunol       Date:  2017-08-04

3.  Apicomplexan parasite, Eimeria falciformis, co-opts host tryptophan catabolism for life cycle progression in mouse.

Authors:  Manuela Schmid; Maik J Lehmann; Richard Lucius; Nishith Gupta
Journal:  J Biol Chem       Date:  2012-04-25       Impact factor: 5.157

4.  TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice.

Authors:  Line S Reinert; Louis Harder; Christian K Holm; Marie B Iversen; Kristy A Horan; Frederik Dagnæs-Hansen; Benedicte P Ulhøi; Thomas H Holm; Trine H Mogensen; Trevor Owens; Jens R Nyengaard; Allan R Thomsen; Søren R Paludan
Journal:  J Clin Invest       Date:  2012-03-19       Impact factor: 14.808

5.  Mouse pancreatic islets are resistant to indoleamine 2,3 dioxygenase-induced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function.

Authors:  Reza B Jalili; Farshad Forouzandeh; Alireza Moeenrezakhanlou; Gina R Rayat; Ray V Rajotte; Hasan Uludag; Aziz Ghahary
Journal:  Am J Pathol       Date:  2008-12-12       Impact factor: 4.307

6.  Differential effect of type I and type II interferons on neopterin production and amino acid metabolism in human astrocyte-derived cells.

Authors:  Oscar D Cano; Gabriele Neurauter; Dietmar Fuchs; Gene M Shearer; Adriano Boasso
Journal:  Neurosci Lett       Date:  2008-04-18       Impact factor: 3.046

Review 7.  The importance of NAD in multiple sclerosis.

Authors:  W Todd Penberthy; Ikuo Tsunoda
Journal:  Curr Pharm Des       Date:  2009       Impact factor: 3.116

8.  Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.

Authors:  David H Munn; Madhav D Sharma; Deyan Hou; Babak Baban; Jeffrey R Lee; Scott J Antonia; Jane L Messina; Phillip Chandler; Pandelakis A Koni; Andrew L Mellor
Journal:  J Clin Invest       Date:  2004-07       Impact factor: 14.808

9.  Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1-/- mice.

Authors:  Linnéa Asp; Maria Holtze; Susan B Powell; Håkan Karlsson; Sophie Erhardt
Journal:  Int J Neuropsychopharmacol       Date:  2009-07-17       Impact factor: 5.176

Review 10.  IDO: a double-edged sword for T(H)1/T(H)2 regulation.

Authors:  Hui Xu; Guang-Xian Zhang; Bogoljub Ciric; Abdolmohamad Rostami
Journal:  Immunol Lett       Date:  2008-09-29       Impact factor: 3.685
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