| Literature DB >> 1492368 |
Abstract
Chromatin diminution in Parascaris and Ascaris represents the classical case of a developmentally programmed genome rearrangement. The process is very specific with respect to ontogenetic timing and chromosomal localization, and involves chromosomal breakage, new telomere formation and DNA degradation. Recent evidence from Ascaris lumbricoides var. suum suggests that chromatin diminution might have a function in gene regulation.Entities:
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Year: 1992 PMID: 1492368 DOI: 10.1016/0168-9525(92)90326-y
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639