Literature DB >> 1490494

Lamotrigine as an add-on drug in the management of Lennox-Gastaut syndrome.

P L Timmings1, A Richens.   

Abstract

We report our experience with lamotrigine add-on therapy in the treatment of 11 patients with Lennox-Gastaut syndrome. Lamotrigine is a novel antiepileptic drug, chemically unrelated to the major anticonvulsants in current use. Ten patients experienced a > 50% reduction in seizure frequency, 1 patient experienced no change in seizure frequency. All patients tolerated lamotrigine satisfactorily and no side-effects were reported.

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Year:  1992        PMID: 1490494     DOI: 10.1159/000116849

Source DB:  PubMed          Journal:  Eur Neurol        ISSN: 0014-3022            Impact factor:   1.710


  11 in total

Review 1.  Newer anti-epileptic drugs.

Authors:  S Aneja; R W Newton
Journal:  Indian J Pediatr       Date:  1996 Mar-Apr       Impact factor: 1.967

Review 2.  Medical management of Lennox-Gastaut syndrome.

Authors:  Aspasia Michoulas; Kevin Farrell
Journal:  CNS Drugs       Date:  2010-05       Impact factor: 5.749

Review 3.  Diagnosis and treatment of epilepsy in children and adolescents.

Authors:  L D Morton; J M Pellock
Journal:  Drugs       Date:  1996-03       Impact factor: 9.546

Review 4.  Lamotrigine. A review of its use in childhood epilepsy.

Authors:  C R Culy; K L Goa
Journal:  Paediatr Drugs       Date:  2000 Jul-Aug       Impact factor: 3.022

5.  Childhood Epilepsy : Current Therapeutic Recommendations.

Authors:  J T Gilman; M Duchowny
Journal:  CNS Drugs       Date:  1994-03       Impact factor: 5.749

Review 6.  Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy.

Authors:  K L Goa; S R Ross; P Chrisp
Journal:  Drugs       Date:  1993-07       Impact factor: 9.546

Review 7.  Guidelines for treating epilepsy in the age of felbamate, vigabatrin, lamotrigine, and gabapentin.

Authors:  K D Laxer
Journal:  West J Med       Date:  1994-09

Review 8.  Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy.

Authors:  A Fitton; K L Goa
Journal:  Drugs       Date:  1995-10       Impact factor: 9.546

9.  Current and emerging treatments for absence seizures in young patients.

Authors:  Pascal Vrielynck
Journal:  Neuropsychiatr Dis Treat       Date:  2013-07-15       Impact factor: 2.570

10.  Treatment of Lennox-Gastaut syndrome: overview and recent findings.

Authors:  Kenou van Rijckevorsel
Journal:  Neuropsychiatr Dis Treat       Date:  2008-12       Impact factor: 2.570

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