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Literature DB >> 14861373

Adaptation of a Lansing strain of poliomyelitis virus to newborn mice.

Abstract

By means of rapid serial passages, including 3 successive "blind" passages, the MEF1 strain, a Lansing-type poliomyelitis virus, has been adapted to new-born mice. The virus can readily be propagated in newborn mice, in which fully adapted virus induces in almost all inoculated animals the experimental disease, resulting in a much greater infectivity for the central nervous system and a uniformly short and regular incubation period.

Entities: Disease Gene Species

Keywords: POLIOMYELITIS

Mesh：

Year: 1951 PMID： 14861373 PMCID： PMC2136100 DOI： 10.1084/jem.94.2.111

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

11 in total

1. Additional properties of the MEFI strain of poliomyelitis virus, especially with reference to attempts at cultivation in the chick embryo.

Authors: R H YAGER; P K OLITSKY; O LAHELLE
Journal: J Bacteriol Date: 1949-07 Impact factor: 3.490

2. TRANSMISSION TO RODENTS OF LANSING TYPE POLIOMYELITIS VIRUS ORIGINATING IN THE MIDDLE EAST.

Authors: R W Schlesinger; I M Morgan; P K Olitsky
Journal: Science Date: 1943-11-19 Impact factor: 47.728

3. Some observations on the pathogenesis of eastern equine encephalomyelitis and louping-ill in young and old animals, with special reference to routes of entry of the viruses into the nervous system.

Authors: E W HURST
Journal: J Comp Pathol Date: 1950-10 Impact factor: 1.311

8. AN ACQUIRED RESISTANCE OF GROWING ANIMALS TO CERTAIN NEUROTROPIC VIRUSES IN THE ABSENCE OF HUMORAL ANTIBODIES OR PREVIOUS EXPOSURE TO INFECTION.

Authors: P K Olitsky; A B Sabin; H R Cox
Journal: J Exp Med Date: 1936-10-31 Impact factor: 14.307

9. INFLUENCE OF AGE FACTORS ON SUSCEPTIBILITY OF MICE TO RABIES VIRUS.

Authors: J Casals
Journal: J Exp Med Date: 1940-09-30 Impact factor: 14.307

10. INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : I. A COMPARISON OF THE TWO ROUTES IN PROTECTION TESTS.

Authors: P K Olitsky; C G Harford
Journal: J Exp Med Date: 1938-07-31 Impact factor: 14.307

7 in total

1. Studies of a Coxsackie virus antigenically related to ECHO 9 virus and associated with an epidemic of aseptic meningitis with exanthem.

Authors: D A TYRRELL; S K CLARKE; R B HEATH; R C CURRAN; T S BESWICK; L WOLMAN
Journal: Br J Exp Pathol Date: 1958-04

Adaptation of a Lansing strain of poliomyelitis virus to newborn mice.

1. Additional properties of the MEFI strain of poliomyelitis virus, especially with reference to attempts at cultivation in the chick embryo.

2. TRANSMISSION TO RODENTS OF LANSING TYPE POLIOMYELITIS VIRUS ORIGINATING IN THE MIDDLE EAST.

3. Some observations on the pathogenesis of eastern equine encephalomyelitis and louping-ill in young and old animals, with special reference to routes of entry of the viruses into the nervous system.

4. A complement-fixation test for poliomyelitis virus.

5. Preservation of neurotropic viruses.

6. CONSTITUTIONAL BARRIERS TO INVOLVEMENT OF THE NERVOUS SYSTEM BY CERTAIN VIRUSES.

7. A MOUSE TEST FOR MEASURING THE IMMUNIZING POTENCY OF ANTIRABIES VACCINES.

8. AN ACQUIRED RESISTANCE OF GROWING ANIMALS TO CERTAIN NEUROTROPIC VIRUSES IN THE ABSENCE OF HUMORAL ANTIBODIES OR PREVIOUS EXPOSURE TO INFECTION.

9. INFLUENCE OF AGE FACTORS ON SUSCEPTIBILITY OF MICE TO RABIES VIRUS.

10. INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : I. A COMPARISON OF THE TWO ROUTES IN PROTECTION TESTS.

1. Studies of a Coxsackie virus antigenically related to ECHO 9 virus and associated with an epidemic of aseptic meningitis with exanthem.

2. Immunization against poliomyelitis.

3. Poliomyelitis in Southendon-Sea in 1952.

4. Development, persistence, and significance of type 2, poliomyelitis complement-fixing antibody in man.

5. The intracellular localization of poliomyelitis virus.

6. Complement-fixing antibodies to type 2 (Lansing) poliomyelitis virus in a normal population of a subtropical area.

7. A specific complement-fixation test for infection with poliomyelitis virus.