Literature DB >> 1484892

Effects of three compounds extracted from Morinda lucida on Plasmodium falciparum.

K Koumaglo1, M Gbeassor, O Nikabu, C de Souza, W Werner.   

Abstract

The effects of three compounds, digitolutein (1), rubiadin 1-methyl ether (2) and damnacanthal (3) extracted from the stem bark and the roots of Morinda lucida Benth. on the growth of Plasmodium falciparum in vitro were investigated. The number of parasites (schizonts) decreased significantly in a dose-dependent manner, and 100% of inhibition was obtained with 30 to 40 micrograms of each compound tested. The IC50 values were calculated.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1484892     DOI： 10.1055/s-2006-961543

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  12 in total

1.  The antiplasmodial agents of the stem bark of Entandrophragma angolense (Meliaceae).

Authors:  Jean Bickii; Guy Raymond Feuya Tchouya; Jean Claude Tchouankeu; Etienne Tsamo
Journal:  Afr J Tradit Complement Altern Med       Date:  2006-11-13

2.  Antimalarial activity in crude extracts of some Cameroonian medicinal plants.

Authors:  Jean Bickii; Guy Raymond Feuya Tchouya; Jean Claude Tchouankeu; Etienne Tsamo
Journal:  Afr J Tradit Complement Altern Med       Date:  2006-08-28

3.  In vivo antimalarial evaluation of MAMA decoction on Plasmodium berghei in mice.

Authors:  Awodayo O Adepiti; Anthony A Elujoba; Oluseye O Bolaji
Journal:  Parasitol Res       Date:  2013-11-22       Impact factor: 2.289

4.  Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection.

Authors:  M Chen; T G Theander; S B Christensen; L Hviid; L Zhai; A Kharazmi
Journal:  Antimicrob Agents Chemother       Date:  1994-07       Impact factor: 5.191

5.  Insecticidal activity and chemical composition of the Morinda lucida essential oil against pulse beetle Callosobruchus maculatus.

Authors:  Moses S Owolabi; Eduardo Padilla-Camberos; Akintayo L Ogundajo; Isiaka A Ogunwande; Guido Flamini; Olaniyi K Yusuff; Kirk Allen; Karen Isabel Flores-Fernandez; Jose Miguel Flores-Fernandez
Journal:  ScientificWorldJournal       Date:  2014-07-20

6.  Microbial Synthesis of Non-Natural Anthraquinone Glucosides Displaying Superior Antiproliferative Properties.

Authors:  Trang Thi Huyen Nguyen; Ramesh Prasad Pandey; Prakash Parajuli; Jang Mi Han; Hye Jin Jung; Yong Il Park; Jae Kyung Sohng
Journal:  Molecules       Date:  2018-08-28       Impact factor: 4.411

7.  In vitro anti-Onchocerca ochengi activities of extracts and chromatographic fractions of Craterispermum laurinum and Morinda lucida.

Authors:  Moses Samje; Jonathan Metuge; James Mbah; Brice Nguesson; Fidelis Cho-Ngwa
Journal:  BMC Complement Altern Med       Date:  2014-09-01       Impact factor: 3.659

8.  Antitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth.

Authors:  Kofi D Kwofie; Nguyen Huu Tung; Mitsuko Suzuki-Ohashi; Michael Amoa-Bosompem; Richard Adegle; Maxwell M Sakyiamah; Frederick Ayertey; Kofi Baffour-Awuah Owusu; Isaac Tuffour; Philip Atchoglo; Kwadwo K Frempong; William K Anyan; Takuhiro Uto; Osamu Morinaga; Taizo Yamashita; Frederic Aboagye; Alfred A Appiah; Regina Appiah-Opong; Alexander K Nyarko; Yasuchika Yamaguchi; Dominic Edoh; Kwadwo A Koram; Shoji Yamaoka; Daniel A Boakye; Nobuo Ohta; Yukihiro Shoyama; Irene Ayi
Journal:  Antimicrob Agents Chemother       Date:  2016-05-23       Impact factor: 5.191

9.  Ethnobotanical Study of Medicinal Plants Used for the Treatment of Malaria in the Plateau Region, Togo.

Authors:  Kodjovi Agbodeka; Holaly E Gbekley; Simplice D Karou; Kokou Anani; Amegnona Agbonon; Tchadjobo Tchacondo; Komlan Batawila; Jacques Simpore; Messanvi Gbeassor
Journal:  Pharmacognosy Res       Date:  2016-03

10.  Antiosteoporotic activity of anthraquinones from Morinda officinalis on osteoblasts and osteoclasts.

Authors:  Yan-Bin Wu; Cheng-Jian Zheng; Lu-Ping Qin; Lian-Na Sun; Ting Han; Lei Jiao; Qiao-Yan Zhang; Jin-Zhong Wu
Journal:  Molecules       Date:  2009-01-23       Impact factor: 4.411
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.