| Literature DB >> 1479747 |
T Shikimi1, K Hattori, S Takaori.
Abstract
A human urinary trypsin inhibitor, urinastatin (UT)-like immunoreactive substance with trypsin inhibitory activity, was demonstrated in certain brain regions in rats, especially the cerebral cortex, hippocampus and hypothalamus. Although this UT-like substance in the rat brain displayed an N-terminal amino acid sequence similar to that of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), it did not show any GAPDH activity. These results indicate that the UT-like substance in the rat brain is a protein different from GAPDH and indicates a localized distribution within certain brain regions partly related to learning and memory.Entities:
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Year: 1992 PMID: 1479747 DOI: 10.1254/jjp.60.97
Source DB: PubMed Journal: Jpn J Pharmacol ISSN: 0021-5198