| Literature DB >> 1479402 |
T Petterson1, I A MacFarlane, J M MacKenzie, M D Shaw.
Abstract
A man with a prolactin secreting pituitary carcinoma was treated by surgery and radiotherapy. Persistent hyperprolactinaemia partially responded to oral bromocriptine for four years. Serum prolactin then rose considerably with rapid, invasive tumour recurrence. Cytotoxic chemotherapy halted tumour progression for twelve months before fatal spread throughout the brain. Failure to normalise serum prolactin with bromocriptine may precede an aggressive course in patients with prolactinoma.Entities:
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Year: 1992 PMID: 1479402 PMCID: PMC1015342 DOI: 10.1136/jnnp.55.12.1205
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN: 0022-3050 Impact factor: 10.154