Literature DB >> 14759758

Back pain--individual and genetic factors.

Charlotte Leboeuf-Yde1.   

Abstract

BACKGROUND: In research, back pain can be classified in several ways. This presentation will deal with 'self-reported back pain', which is a proxy measure of 'having back pain'. The terms 'individual factors' cover many aspects of human life. They also interact with external factors, such as work and environment. Back pain is prevalent at all ages, although the incidence (onset) probably is highest in the early teens. Causative and modifying factors may differ throughout life and it is not sure that the etiology of 'back pain' remains the same. If we are to prevent and treat back pain in an efficient way, it is essential that we understand the circumstances that bring it on or prevent it from getting better. The mode of action would depend on whether the responsibility lies mainly with the individual, for example through a change of life-style, or with others, for example by altering the work place.
METHOD: My presentation will consist of three elements, evidence obtained from: (1). systematic literature reviews, (2). epidemiologic studies, and (3). genetic epidemiologic studies. All the information presented is based on own work and pertains to children/adolescents and adults, mostly in relation to low back pain (LBP). The evidence will be reviewed in the light of 'the weight of evidence' on the topics of: genetics, sedentary life-style, type of work and imaging findings. Also factors relating to social class and physical/psychological robustness will be discussed.
RESULTS: There is evidence for a relatively strong genetic component to LBP, both in the young and in adults. Hard work is strongly linked to LBP and there is a moderate link with abnormal imaging findings (spinal pathology in the young and discal degeneration in both the young and the adults). In addition, a weak psychological and psychological constitution appears to be of interest, at least in the young. However, there is no evidence for a causal link between a sedentary life-style and LBP, neither in the young nor in the adults.
CONCLUSIONS: Some myths in the area of back pain are dispelled by the evidence in relation to personal and genetic factors and some new elements need considering. It is suggested that we should look for populations at risk, rather than looking for risk factors. Populations at risk would consist of people with a weak psychological and physiological constitution, who more easily than others may develop long lasting back pain as well as other CLINICAL SIGNIFICANCE: Early identification of high risk populations will allow for a selective primary and secondary preventive approach.

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Mesh:

Year:  2004        PMID: 14759758     DOI: 10.1016/j.jelekin.2003.09.019

Source DB:  PubMed          Journal:  J Electromyogr Kinesiol        ISSN: 1050-6411            Impact factor:   2.368


  12 in total

1.  Immune responses to low back pain risk factors.

Authors:  Riley E Splittstoesser; William S Marras; Thomas M Best
Journal:  Work       Date:  2012

2.  Symptomatology of recurrent low back pain in nursing and administrative professions.

Authors:  Peter Schenk; Thomas Läubli; Juerg Hodler; Andreas Klipstein
Journal:  Eur Spine J       Date:  2007-07-05       Impact factor: 3.134

3.  Clinicians' views on factors that trigger a sudden onset of low back pain.

Authors:  Daniel Steffens; Chris G Maher; Manuela L Ferreira; Mark J Hancock; Timothy Glass; Jane Latimer
Journal:  Eur Spine J       Date:  2013-12-08       Impact factor: 3.134

4.  Multivariable modeling of factors associated with spinal pain in young adolescence.

Authors:  Mieke Dolphens; Stijn Vansteelandt; Barbara Cagnie; Andry Vleeming; Jo Nijs; Guy Vanderstraeten; Lieven Danneels
Journal:  Eur Spine J       Date:  2016-06-08       Impact factor: 3.134

5.  Prevalence, consequences and predictors of low back pain among nurses in a tertiary care setting.

Authors:  Sameh M Abolfotouh; Karim Mahmoud; Khaled Faraj; Gemeh Moammer; Abir ElSayed; Mostafa A Abolfotouh
Journal:  Int Orthop       Date:  2015-07-19       Impact factor: 3.075

6.  [Amplified back pain and comorbidity in the population].

Authors:  A Hüppe; H Raspe
Journal:  Schmerz       Date:  2009-06       Impact factor: 1.107

7.  Are psychological symptoms a risk factor for musculoskeletal pain in adolescents?

Authors:  Alessandro Andreucci; Paul Campbell; Kate M Dunn
Journal:  Eur J Pediatr       Date:  2021-03-02       Impact factor: 3.183

8.  Cumulative low back load at work as a risk factor of low back pain: a prospective cohort study.

Authors:  Pieter Coenen; Idsart Kingma; Cécile R L Boot; Jos W R Twisk; Paulien M Bongers; Jaap H van Dieën
Journal:  J Occup Rehabil       Date:  2013-03

9.  Is objectively measured sitting time associated with low back pain? A cross-sectional investigation in the NOMAD study.

Authors:  Nidhi Gupta; Caroline Stordal Christiansen; David M Hallman; Mette Korshøj; Isabella Gomes Carneiro; Andreas Holtermann
Journal:  PLoS One       Date:  2015-03-25       Impact factor: 3.240

10.  Unspecific chronic low back pain - a simple functional classification tested in a case series of patients with spinal deformities.

Authors:  Hans-Rudolf Weiss; Mario Werkmann
Journal:  Scoliosis       Date:  2009-02-17
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