Literature DB >> 14759459

Biomechanical study of a poly-L-lactide (PLLA) sternal pin in sternal closure after cardiothoracic surgery.

Takeshi Saito1, Atsushi Iguchi, Masahiro Sakurai, Koichi Tabayashi.   

Abstract

BACKGROUND: Stainless steel wiring is currently the standard method of median sternotomy closure but it has been reported that sufficient stiffness is not obtained by the method in anterior-posterior and cranial-caudal directions. A bioabsorbable Poly-L-Lactide (PLLA) sternal pin has been developed as an additive material for sternal closure. We biomechanically examined the effectiveness of a PLLA sternal pin in the two directions by using the sternum of a juvenile pig.
METHODS: Juvenile pigs 14-17 kg weight were used. After the sternum was extirpated it was cut into two pieces at the midline. In a wire fixation group the pieces were fixed by two stainless wires. In a wire and intrasternal fixation group a hole was drilled into the bone marrow and a PLLA sternal pin for an infant was set into the hole. Then the both sides of the wired sternum were fixed tightly at the testing machine and the shear stress was forced into the one side. The shear stress was forced in anterior-posterior and cranial-caudal directions.
RESULTS: In an anterior-posterior direction, the stiffness was 13.84 +/- 1.84 (N/mm) in a wire and intrasternal fixation group and 7.00 +/- 2.71 (N/mm) in a wire fixation group (p = 0.0002). In a cranial-caudal direction it was 10.61 +/- 4.88 (N/mm) and 4.38 +/- 2.12 (N/mm), respectively (p = 0.03).
CONCLUSIONS: The use of a PLLA sternal pin as an additive material to steel wiring was effective in preventing the displacement of the sternum in both directions. Our data showed that closure technique using a sternal pin would provide adequate fixation.

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Year:  2004        PMID: 14759459     DOI: 10.1016/S0003-4975(03)01341-9

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  8 in total

1.  In vitro study of drug-eluting stent coatings based on poly(L-lactide) incorporating cyclosporine A - drug release, polymer degradation and mechanical integrity.

Authors:  Katrin Sternberg; Sven Kramer; Claudia Nischan; Niels Grabow; Thomas Langer; Gerhard Hennighausen; Klaus-Peter Schmitz
Journal:  J Mater Sci Mater Med       Date:  2007-03-27       Impact factor: 3.896

2.  Comparison of straight median sternotomy and interlocking sternotomy with respect to biomechanical stability.

Authors:  Fatih Küçükdurmaz; Ismail Ağır; Murat Bezer
Journal:  World J Orthop       Date:  2013-07-18

3.  Absorbable sternal pins improve sternal closure stability within a small deviation.

Authors:  Hiroshi Koshiyama; Kenji Yamazaki
Journal:  Gen Thorac Cardiovasc Surg       Date:  2015-02-27

Review 4.  Sternal wound closure in the current era: the need of a tailored approach.

Authors:  Antonio Nenna; Francesco Nappi; Jennifer Dougal; Umberto Satriano; Camilla Chello; Ciro Mastroianni; Mario Lusini; Massimo Chello; Cristiano Spadaccio
Journal:  Gen Thorac Cardiovasc Surg       Date:  2019-09-17

Review 5.  Review of Biomechanical Studies and Finite Element Modeling of Sternal Closure Using Bio-Active Adhesives.

Authors:  Amatulraheem Al-Abassi; Marcello Papini; Mark Towler
Journal:  Bioengineering (Basel)       Date:  2022-05-03

6.  Clinical assessment of efficacy of poly-L-lactide sternal pin on sternal stability and post-operative pain: a prospective randomized trial in cardiovascular surgery.

Authors:  Shingo Takahara; Konosuke Sasaki; Takeshi Saito; Kei Sakuma; Hidenori Fujiwara; Ichiro Yoshioka; Kiichiro Kumagai; Wenyu Sun; Kei Takase; Yoshikatsu Saiki
Journal:  J Thorac Dis       Date:  2022-01       Impact factor: 2.895

Review 7.  Titanium or Biodegradable Osteosynthesis in Maxillofacial Surgery? In Vitro and In Vivo Performances.

Authors:  Barzi Gareb; Nico B Van Bakelen; Arjan Vissink; Ruud R M Bos; Baucke Van Minnen
Journal:  Polymers (Basel)       Date:  2022-07-07       Impact factor: 4.967

8.  Evaluation of physical and mechanical properties of porous poly (ethylene glycol)-co-(L-lactic acid) hydrogels during degradation.

Authors:  Yu-Chieh Chiu; Sevi Kocagöz; Jeffery C Larson; Eric M Brey
Journal:  PLoS One       Date:  2013-04-09       Impact factor: 3.240

  8 in total

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