Literature DB >> 14754457

Recent studies on natural products as anticancer agents.

Angel G Ravelo1, Ana Estévez-Braun, Haydee Chávez-Orellana, Elisa Pérez-Sacau, Dulce Mesa-Siverio.   

Abstract

Cancer will be the major cause of death in the 21st century and natural products should provide novel and more effective anticancer agents. This review deals with new natural molecules liable to become anticancer drugs, as well as recent specific strategies for a selective treatment of cancer. The introduction presents the current state of the art on anticancer research. Beside, in the following subheadings we summarize our research on cytotoxic natural quinone methide-triperpenes and their analogues. We also discuss our results on the anti-tumour promoting activity of natural naphthoquinones and their derivatives.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14754457     DOI： 10.2174/1568026043451500

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  9 in total

1.  Synergistic TRAIL sensitizers from Barleria alluaudii and Diospyros maritima.

Authors:  Emily L Whitson; Han Sun; Cheryl L Thomas; Curtis J Henrich; Thomas J Sayers; James B McMahon; Christian Griesinger; Tawnya C McKee
Journal:  J Nat Prod       Date:  2012-02-07       Impact factor: 4.050

2.  Theoretical investigation of the radical scavenging activity of shikonin and acylshikonin derivatives.

Authors:  Ruifa Jin; Yin Bai
Journal:  J Mol Model       Date:  2011-07-15       Impact factor: 1.810

3.  A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products.

Authors:  A Estévez-Braun; A G Ravelo; E Pérez-Sacau; J C Lacal
Journal:  Clin Transl Oncol       Date:  2014-12-04       Impact factor: 3.405

4.  Oxyrane derivative of alpha-lapachone is potent growth inhibitor of Trypanosoma cruzi epimastigote forms.

Authors:  Alessandra Jorqueira; Robson M Gouvêa; Vitor F Ferreira; Milton N da Silva; Maria C B V de Souza; Aline A Zuma; Danielle F B Cavalcanti; Humberto P Araújo; Dilvani O Santos; Saulo C Bourguignon
Journal:  Parasitol Res       Date:  2006-04-05       Impact factor: 2.383

5.  Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II.

Authors:  Huanli Xu; Qunying Chen; Hong Wang; Pingxiang Xu; Ru Yuan; Xiaorong Li; Lu Bai; Ming Xue
Journal:  J Exp Clin Cancer Res       Date:  2016-11-16

Review 6.  The Application of Embelin for Cancer Prevention and Therapy.

Authors:  Jeong-Hyeon Ko; Seok-Geun Lee; Woong Mo Yang; Jae-Young Um; Gautam Sethi; Srishti Mishra; Muthu K Shanmugam; Kwang Seok Ahn
Journal:  Molecules       Date:  2018-03-09       Impact factor: 4.411

7.  Antiproliferative evaluation of isofuranodiene on breast and prostate cancer cell lines.

Authors:  Michela Buccioni; Diego Dal Ben; Catia Lambertucci; Filippo Maggi; Fabrizio Papa; Ajiroghene Thomas; Claudia Santinelli; Gabriella Marucci
Journal:  ScientificWorldJournal       Date:  2014-05-22

8.  Effect of Phyllanthus amarus on serum biochemical changes in azaserine induced pancreatic cancer in Wistar rats.

Authors:  Ankit S Prajapati; Sunant K Raval; Suprita Sinha; Tapan N Varia; Parimal H Mashiyava
Journal:  Vet World       Date:  2015-08-07

9.  A novel 1,4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells.

Authors:  Didem Karakaş; Remzi Okan Akar; Zeliha Gökmen; Nahide Gülşah Deniz; Engin Ulukaya
Journal:  Turk J Biol       Date:  2019-08-05
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.