Literature DB >> 14748591

A novel approach to 2-arylated quinolines: electrocyclization of alkynyl imines via vinylidene complexes.

Kenichiro Sangu1, Kohei Fuchibe, Takahiko Akiyama.   

Abstract

[reaction: see text] Alkynyl imines underwent [4 + 2] electrocyclization in the presence of 20 mol % W(CO)(5)(THF) to give 2-arylated quinolines in good yields. A deuterium labeling study suggests that the reaction proceeds via a tungsten vinylidene complex.

Entities:  

Year:  2004        PMID： 14748591     DOI： 10.1021/ol036190a

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  Enantioselective total synthesis and biological evaluation of (+)-kibdelone A and a tetrahydroxanthone analogue.

Authors:  Dana K Winter; Mary Ann Endoma-Arias; Tomas Hudlicky; John A Beutler; John A Porco
Journal:  J Org Chem       Date:  2013-07-23       Impact factor: 4.354

Review 2.  Metal vinylidenes as catalytic species in organic reactions.

Authors:  Barry M Trost; Andrew McClory
Journal:  Chem Asian J       Date:  2008-02-01

3.  One-pot phosphine-catalyzed syntheses of quinolines.

Authors:  San Khong; Ohyun Kwon
Journal:  J Org Chem       Date:  2012-09-06       Impact factor: 4.354

4.  Synthesis and docking analysis of new heterocyclic system of tetrazolo[5',1':2,3][1,3,4]thiadiazepino [7,6-b]quinolines as aldose reductase inhibitors.

Authors:  Mohammad Saadatmandzadeh; Mohammad Rahimizadeh; Hossein Eshghi; Mojtaba Sankian
Journal:  Iran J Basic Med Sci       Date:  2014-09       Impact factor: 2.699

5.  Synthesis and Docking Analysis of New Heterocyclic System N1, N4-bis (2-chloroquinolin-3-yl) methylene) benzene-1, 4-diamine as Potential Human AKT1 Inhibitor.

Authors:  Sohrab Ghanei; Jalil Lari; Hossein Eshghi; Mohammad Saadatmandzadeh
Journal:  Iran J Pharm Res       Date:  2016       Impact factor: 1.696

6.  4,6-Dihydroxysalicylic Acid-Catalyzed Oxidative Condensation of Benzylic Amines and Aromatic Ketones for the Preparation of 2,4,6-Trisubstituted Pyridines and Its Application to Metal-Free Synthesis of G-Quadruplex Binding Ligands.

Authors:  Chun-Ping Dong; Shintaro Kodama; Akihiro Nomoto; Michio Ueshima; Akiya Ogawa
Journal:  ACS Omega       Date:  2019-05-23

7.  Facile One-Pot Synthesis of Functionalized Quinoline-Fused Fluorescent Dihydro/Spiro-quinazolinone Derivatives.

Authors:  Kevin George; Pavithra Elavarasan; Shanmugam Ponnusamy; Kannadasan Sathananthan
Journal:  ACS Omega       Date:  2022-06-09
  7 in total

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