Literature DB >> 14747015

More plastids in human parasites?

Ross F Waller1, Malcolm J McConville, Geoffrey I McFadden.   

Abstract

Trypanosomatid parasites are disease agents with an extraordinarily broad host range including humans, livestock and plants. Recent work has revealed that trypanosomatids harbour numerous genes sharing apparent common ancestry with plants and/or bacteria. Although there is no evidence of a plastid (chloroplast-like organelle) in trypanosomatids, the presence of such genes suggests lateral gene transfer from some photosynthetic organism(s) during trypanosomatid evolution. Remarkably, many products of these horizontally acquired genes now function in the glycosome, a highly modified peroxisome unique to trypanosomatids and their near relatives.

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Year:  2004        PMID: 14747015     DOI: 10.1016/j.pt.2003.10.018

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  3 in total

1.  Homologues of Arabidopsis Microtubule-Associated AIR9 in Trypanosomatid Parasites: Hints on Evolution and Function.

Authors:  Henrik Buschmann; Luis Sanchez-Pulido; Miguel A Andrade-Navarro; Clive W Lloyd
Journal:  Plant Signal Behav       Date:  2007-07

2.  Maturation of the unusual single-cysteine (XXXCH) mitochondrial c-type cytochromes found in trypanosomatids must occur through a novel biogenesis pathway.

Authors:  James W A Allen; Michael L Ginger; Stuart J Ferguson
Journal:  Biochem J       Date:  2004-11-01       Impact factor: 3.857

3.  A novel subfamily of monomeric inorganic pyrophosphatases in photosynthetic eukaryotes.

Authors:  María R Gómez-García; Manuel Losada; Aurelio Serrano
Journal:  Biochem J       Date:  2006-04-01       Impact factor: 3.857

  3 in total

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