Literature DB >> 14745073

Zonisamide treatment for symptomatic infantile spasms.

Timothy E Lotze1, Angus A Wilfong.   

Abstract

The authors evaluated zonisamide for symptomatic infantile spasms in 23 patients. Spasm cessation, EEG evolution, and tolerability were assessed for a mean duration of 6.5 months. Six patients (26%) had complete control with cessation of spasms and clearing of hypsarrhythmia. Mean latency time from onset of zonisamide treatment to complete spasm control was 19 days. There were no discontinuations due to adverse effects.

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Year:  2004        PMID: 14745073     DOI: 10.1212/01.wnl.0000103284.73495.35

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  12 in total

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