Literature DB >> 14744439

Unraveling V(D)J recombination; insights into gene regulation.

David Jung1, Frederick W Alt.   

Abstract

V(D)J recombination assembles antigen receptor genes from component gene segments. We review findings that have shaped our current understanding of this remarkable mechanism, with a focus on two major reports--the first detailed comparison of germline and rearranged antigen receptor loci and the discovery of the recombination activating gene-1.

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Year:  2004        PMID： 14744439     DOI： 10.1016/s0092-8674(04)00039-x

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  129 in total

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Authors:  Larry J Dishaw; Robert N Haire; Gary W Litman
Journal:  Brief Funct Genomics       Date:  2012-03-07       Impact factor: 4.241

2.  Parole terms for a killer: directing caspase3/CAD induced DNA strand breaks to coordinate changes in gene expression.

Authors:  Brian D Larsen; Lynn A Megeney
Journal:  Cell Cycle       Date:  2010-08-01       Impact factor: 4.534

Review 3.  Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications.

Authors:  Bao Q Vuong; Jayanta Chaudhuri
Journal:  Semin Immunol       Date:  2012-07-06       Impact factor: 11.130

4.  Integrated mimicry of B cell antibody mutagenesis using yeast homologous recombination.

Authors:  Jeffrey S Swers; Yik A Yeung; K Dane Wittrup
Journal:  Mol Biotechnol       Date:  2011-01       Impact factor: 2.695

5.  Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3.

Authors:  Jeremy A Goettel; Subhabrata Biswas; Willem S Lexmond; Ada Yeste; Laura Passerini; Bonny Patel; Siyoung Yang; Jiusong Sun; Jodie Ouahed; Dror S Shouval; Katelyn J McCann; Bruce H Horwitz; Diane Mathis; Edgar L Milford; Luigi D Notarangelo; Maria-Grazia Roncarolo; Edda Fiebiger; Wayne A Marasco; Rosa Bacchetta; Francisco J Quintana; Sung-Yun Pai; Christoph Klein; Aleixo M Muise; Scott B Snapper
Journal:  Blood       Date:  2015-04-01       Impact factor: 22.113

Review 6.  Reconstructing immune phylogeny: new perspectives.

Authors:  Gary W Litman; John P Cannon; Larry J Dishaw
Journal:  Nat Rev Immunol       Date:  2005-11       Impact factor: 53.106

7.  Elucidation of IgH intronic enhancer functions via germ-line deletion.

Authors:  Thomas Perlot; Frederick W Alt; Craig H Bassing; Heikyung Suh; Eric Pinaud
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-26       Impact factor: 11.205

Review 8.  Prognostic usage of V(H) gene mutation status and its surrogate markers and the role of antigen selection in chronic lymphocytic leukemia.

Authors:  Gerard Tobin; Richard Rosenquist
Journal:  Med Oncol       Date:  2005       Impact factor: 3.064

Review 9.  Evolution of adaptive immunity from transposable elements combined with innate immune systems.

Authors:  Eugene V Koonin; Mart Krupovic
Journal:  Nat Rev Genet       Date:  2014-12-09       Impact factor: 53.242

10.  Functional analysis of histone methyltransferase g9a in B and T lymphocytes.

Authors:  Lance R Thomas; Hiroki Miyashita; Robin Milley Cobb; Steven Pierce; Makoto Tachibana; Elias Hobeika; Michael Reth; Yoichi Shinkai; Eugene M Oltz
Journal:  J Immunol       Date:  2008-07-01       Impact factor: 5.422
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