Literature DB >> 14742153

Novel approach to the application of botulinum toxin to the flexor digitorum superficialis muscle in acquired brain injury.

Michael C Munin1, Brinda K Navalgund, Donna A Levitt, Terry P Breisinger, Ross D Zafonte.   

Abstract

PRIMARY
OBJECTIVE: To determine if the finger flexor mapping technique is useful in the reduction of spasticity when injecting neurotoxin within the flexor digitorum superficialis muscle. RESEARCH
DESIGN: Case series of consecutive persons with acquired brain injury with upper limb spasticity. METHODS AND PROCEDURES: The flexor digitorum superficialis mapping technique was used to determine the optimal location for botulinum toxin A insertion into each belly of the flexor digitorum superficialis. Modified Ashworth Scale (MAS) ratings were recorded pre- and post-flexor digitorum superficialis injection from 17 patients (18 limbs) with upper limb spasticity. MAIN OUTCOMES AND
RESULTS: The pre-injection mean MAS score was 3.0 +/- 0.7 and the post-injection mean MAS score was 1.5 +/- 0.9 for this cohort. Using the Wilcoxon matched pairs signed rank test, the mean MAS finger flexor scores decreased significantly ( p < 0.05). No adverse events were noted with the procedure.
CONCLUSIONS: This novel technique appears to be feasible and effective for placement of botulinum toxin in the treatment of finger flexor spasticity. Further studies are warranted to compare this method of administration with other injection approaches for the treatment of finger flexor spasticity.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 14742153     DOI: 10.1080/02699050310001617334

Source DB:  PubMed          Journal:  Brain Inj        ISSN: 0269-9052            Impact factor:   2.311


  3 in total

1.  Anatomic localization of motor entry points and accurate regions for botulinum toxin injection in the flexor digitorum superficialis.

Authors:  J F Ye; J H Lee; X C An; C H Lin; B Yue; Seung-Ho Han
Journal:  Surg Radiol Anat       Date:  2011-01-22       Impact factor: 1.246

2.  Cyclic functional electrical stimulation does not enhance gains in hand grasp function when used as an adjunct to onabotulinumtoxinA and task practice therapy: a single-blind, randomized controlled pilot study.

Authors:  Douglas J Weber; Elizabeth R Skidmore; Christian Niyonkuru; Chia-Lin Chang; Lynne M Huber; Michael C Munin
Journal:  Arch Phys Med Rehabil       Date:  2010-05       Impact factor: 3.966

3.  Comparison of surface and ultrasound localization to identify forearm flexor muscles for botulinum toxin injections.

Authors:  M Kristi Henzel; Michael C Munin; Christian Niyonkuru; Elizabeth R Skidmore; Douglas J Weber; Ross D Zafonte
Journal:  PM R       Date:  2010-07       Impact factor: 2.298

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.