Literature DB >> 14740050

Anti-viral cyclam macrocycles : rapid zinc uptake at physiological pH.

Stephen J Paisey1, Peter J Sadler.   

Abstract

NMR and UV-vis spectroscopic studies show that Zn(II) binds to cyclam rapidly at micromolar concentrations, an observation relevant to the anti-viral activity and co-receptor binding of anti-HIV cyclams.

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Year:  2004        PMID： 14740050     DOI： 10.1039/b312752b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  Application of metal coordination chemistry to explore and manipulate cell biology.

Authors:  Kathryn L Haas; Katherine J Franz
Journal:  Chem Rev       Date:  2009-10       Impact factor: 60.622

2.  Protein recognition of macrocycles: binding of anti-HIV metallocyclams to lysozyme.

Authors:  Tina M Hunter; Iain W McNae; Xiangyang Liang; Juraj Bella; Simon Parsons; Malcolm D Walkinshaw; Peter J Sadler
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-08       Impact factor: 11.205

3.  Cyclam-based polymeric copper chelators for gene delivery and potential PET imaging.

Authors:  Jing Li; Yu Zhu; Stuart T Hazeldine; Steven M Firestine; David Oupický
Journal:  Biomacromolecules       Date:  2012-09-25       Impact factor: 6.988

4.  Oxovanadium(IV) cyclam and bicyclam complexes: potential CXCR4 receptor antagonists.

Authors:  Allison Ross; Dinesh C Soares; Danielle Covelli; Christophe Pannecouque; Laura Budd; Anna Collins; Neil Robertson; Simon Parsons; Erik De Clercq; Pierre Kennepohl; Peter J Sadler
Journal:  Inorg Chem       Date:  2010-02-01       Impact factor: 5.165

5.  Diaqua-(1,4,8,11-tetra-aza-cyclo-tetra-deca-ne)nickel(II) fumarate tetra-hydrate.

Authors:  Shao Liang Lim; Chew Hee Ng; Siang Guan Teoh; Wan-Sin Loh; Hoong-Kun Fun
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-06-05
  5 in total

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