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Literature DB >> 14739395

Why do we not all have proteinuria? An update of our current understanding of the glomerular barrier.

Abstract

The key question is not why some patients have proteinuria but rather why not all people have it. In the present review, we will present an update on the glomerular barrier after the recent breakthroughs in podocyte biology. In particular, we will discuss the role of the endothelium, which seems to be a neglected part of the glomerular membrane.

Entities: Disease Species

Mesh：

Year: 2004 PMID： 14739395 DOI： 10.1152/nips.01461.2003

Source DB: PubMed Journal: News Physiol Sci ISSN： 0886-1714

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Cited

22 in total

1. Plasma half-life extension of small recombinant antibodies by fusion to immunoglobulin-binding domains.

Authors: Meike Hutt; Aline Färber-Schwarz; Felix Unverdorben; Fabian Richter; Roland E Kontermann
Journal: J Biol Chem Date: 2011-12-06 Impact factor: 5.157

2. What determines glomerular capillary permeability?

Authors: William M Deen
Journal: J Clin Invest Date: 2004-11 Impact factor: 14.808

3. High glucose causes dysfunction of the human glomerular endothelial glycocalyx.

Authors: A Singh; V Fridén; I Dasgupta; R R Foster; G I Welsh; J E Tooke; B Haraldsson; P W Mathieson; S C Satchell
Journal: Am J Physiol Renal Physiol Date: 2010-10-27

4. Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation.

Authors: Florian Bolze; Andrea Bast; Sabine Mocek; Volker Morath; Detian Yuan; Nadine Rink; Martin Schlapschy; Anika Zimmermann; Mathias Heikenwalder; Arne Skerra; Martin Klingenspor
Journal: Diabetologia Date: 2016-06-07 Impact factor: 10.122

Why do we not all have proteinuria? An update of our current understanding of the glomerular barrier.

1. Plasma half-life extension of small recombinant antibodies by fusion to immunoglobulin-binding domains.

2. What determines glomerular capillary permeability?

3. High glucose causes dysfunction of the human glomerular endothelial glycocalyx.

4. Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation.

5. Organic radical contrast agents for magnetic resonance imaging.

6. Functional and molecular alterations of the glomerular barrier in long-term diabetes in mice.

7. Podocytes use FcRn to clear IgG from the glomerular basement membrane.

Review 8. Losartan chemistry and its effects via AT1 mechanisms in the kidney.

Review 9. The role of the glomerular endothelium in albumin handling.

10. The endothelial lipase protein is promising urinary biomarker for diagnosis of gastric cancer.