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Literature DB >> 14738398

A new phloroglucinol derivative from the brown alga Eisenia bicyclis: potential for the effective treatment of diabetic complications.

Yoshihito Okada¹, Akiko Ishimaru, Ryuichiro Suzuki, Toru Okuyama.

Abstract

A new phloroglucinol derivative (1) and two known compounds (2 and 3) were isolated from the brown alga Eisenia bicyclis. These isolates exhibit inhibitory activity on glycation and alpha-amylase. Their structures were determined on the basis of spectroscopic data.

Entities: Chemical Disease

Mesh：

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Year: 2004 PMID： 14738398 DOI： 10.1021/np030323j

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

14 in total

1. Dieckol, isolated from Ecklonia stolonifera, induces apoptosis in human hepatocellular carcinoma Hep3B cells.

Authors: Jin-Soo Yoon; Anandam Kasin Yadunandam; Soon-Jin Kim; Hee-Chul Woo; Hyeung-Rak Kim; Gun-Do Kim
Journal: J Nat Med Date: 2012-10-09 Impact factor: 2.343

2. Edible seaweed, Eisenia bicyclis, protects retinal ganglion cells death caused by oxidative stress.

Authors: Kyung-A Kim; Sang Min Kim; Suk Woo Kang; Sang Il Jeon; Byung Hun Um; Sang Hoon Jung
Journal: Mar Biotechnol (NY) Date: 2012-05-18 Impact factor: 3.619

3. 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4-dioxin inhibits adipocyte differentiation of 3T3-L1 fibroblasts.

Authors: Chang-Suk Kong; Jung-Ae Kim; Byul-Nim Ahn; Thanh Sang Vo; Na-Young Yoon; Se-Kwon Kim
Journal: Mar Biotechnol (NY) Date: 2009-08-13 Impact factor: 3.619

10. α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activity of Plastoquinones from Marine Brown Alga Sargassum serratifolium.

Authors: Md Yousof Ali; Da Hye Kim; Su Hui Seong; Hyeung-Rak Kim; Hyun Ah Jung; Jae Sue Choi
Journal: Mar Drugs Date: 2017-12-01 Impact factor: 5.118

A new phloroglucinol derivative from the brown alga Eisenia bicyclis: potential for the effective treatment of diabetic complications.

1. Dieckol, isolated from Ecklonia stolonifera, induces apoptosis in human hepatocellular carcinoma Hep3B cells.

2. Edible seaweed, Eisenia bicyclis, protects retinal ganglion cells death caused by oxidative stress.

3. 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4-dioxin inhibits adipocyte differentiation of 3T3-L1 fibroblasts.

4. Protective efficacy of an Ecklonia cava extract used to treat transient focal ischemia of the rat brain.

5. Profiling of the molecular weight and structural isomer abundance of macroalgae-derived phlorotannins.

6. In vitro anti-osteoporosis properties of diverse Korean Drynariae rhizoma phenolic extracts.

Review 7. Marine Organisms with Anti-Diabetes Properties.

8. Anti-inflammatory effect of ethanolic extract from Myagropsis myagroides on murine macrophages and mouse ear edema.

Review 9. Potential Bioactive Compounds from Seaweed for Diabetes Management.

10. α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activity of Plastoquinones from Marine Brown Alga Sargassum serratifolium.