Literature DB >> 14737363

Novel and efficient synthesis of difficult sequence-containing peptides through O-N intramolecular acyl migration reaction of O-acyl isopeptides.

Youhei Sohma1, Masato Sasaki, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso.   

Abstract

A novel and efficient method for the synthesis of difficult sequence-containing peptides has been developed based on the synthesis of O-acyl isopeptides followed by an O-N intramolecular acyl migration reaction, resulting in a remarkable improvement of the yields.

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Year:  2003        PMID: 14737363     DOI: 10.1039/b312129a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  19 in total

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Review 6.  Peptides and peptidomimetics as immunomodulators.

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8.  On the synthesis of conformationally modified peptides through isonitrile chemistry: implications for dealing with polypeptide aggregation.

Authors:  Xiangyang Wu; Peter K Park; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2011-05-03       Impact factor: 15.419

9.  Amide-forming chemical ligation via O-acyl hydroxamic acids.

Authors:  Daniel L Dunkelmann; Yuki Hirata; Kyle A Totaro; Daniel T Cohen; Chi Zhang; Zachary P Gates; Bradley L Pentelute
Journal:  Proc Natl Acad Sci U S A       Date:  2018-03-26       Impact factor: 11.205

10.  Gly25-Ser26 amyloid β-protein structural isomorphs produce distinct Aβ42 conformational dynamics and assembly characteristics.

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Journal:  J Mol Biol       Date:  2014-04-13       Impact factor: 5.469

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