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Literature DB >> 14737344

Carbon-carbon bond cleavage by cytochrome p450(BioI)(CYP107H1).

Abstract

Cytochrome p450(BioI)(CYP107H1) is believed to supply pimelic acid equivalents for biotin biosynthesis in Bacillus subtilis: we report here that the mechanistic pathway adopted by this multifunctional p450 for the in-chain cleavage of fatty acids is via consecutive formation of alcohol and threo-diol intermediates, with the likely absolute configuration of the intermediates also reported.

Entities: Chemical Species

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Year: 2003 PMID： 14737344 DOI： 10.1039/b311652b

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

16 in total

Review 1. Formation and Cleavage of C-C Bonds by Enzymatic Oxidation-Reduction Reactions.

Authors: F Peter Guengerich; Francis K Yoshimoto
Journal: Chem Rev Date: 2018-06-22 Impact factor: 60.622

Review 2. Divergent mechanisms of iron-containing enzymes for hydrocarbon biosynthesis.

Authors: Courtney E Wise; Job L Grant; Jose A Amaya; Steven C Ratigan; Chun H Hsieh; Olivia M Manley; Thomas M Makris
Journal: J Biol Inorg Chem Date: 2016-12-21 Impact factor: 3.358

3. Biotin Synthesis in Ralstonia eutropha H16 Utilizes Pimeloyl Coenzyme A and Can Be Regulated by the Amount of Acceptor Protein.

Authors: Jessica Eggers; Carl Simon Strittmatter; Kira Küsters; Emre Biller; Alexander Steinbüchel
Journal: Appl Environ Microbiol Date: 2020-09-01 Impact factor: 4.792

4. A tris (2-carboxyethyl) phosphine (TCEP) related cleavage on cysteine-containing proteins.

Authors: Peiran Liu; Brian W O'Mara; Bethanne M Warrack; Wei Wu; Yunping Huang; Yihong Zhang; Rulin Zhao; Mei Lin; Michael S Ackerman; Peter K Hocknell; Guodong Chen; Li Tao; Siegfried Rieble; Jack Wang; David B Wang-Iverson; Adrienne A Tymiak; Michael J Grace; Reb J Russell
Journal: J Am Soc Mass Spectrom Date: 2010-01-28 Impact factor: 3.109

10. Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.

Authors: Max J Cryle; Ilme Schlichting
Journal: Proc Natl Acad Sci U S A Date: 2008-10-06 Impact factor: 11.205

Carbon-carbon bond cleavage by cytochrome p450(BioI)(CYP107H1).

Review 1. Formation and Cleavage of C-C Bonds by Enzymatic Oxidation-Reduction Reactions.

Review 2. Divergent mechanisms of iron-containing enzymes for hydrocarbon biosynthesis.

3. Biotin Synthesis in Ralstonia eutropha H16 Utilizes Pimeloyl Coenzyme A and Can Be Regulated by the Amount of Acceptor Protein.

4. A tris (2-carboxyethyl) phosphine (TCEP) related cleavage on cysteine-containing proteins.

5. The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry.

6. Proteomic insights into metabolic adaptations in Alcanivorax borkumensis induced by alkane utilization.

Review 7. Synthesis of the α,ω-dicarboxylic acid precursor of biotin by the canonical fatty acid biosynthetic pathway.

8. Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.

9. The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes.

10. Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.