OBJECTIVE: The effectiveness of topical intranasal steroids (INS) sprays for the treatment of allergic and nonallergic rhinitis may be limited by lack of instruction in the optimal spray technique. To determine whether the technique used affects the efficacy and safety of the product, this review of evidence had the goal of identifying and establishing a preferred method of applying INS sprays. STUDY DESIGN: A MEDLINE search of pertinent literature on 7 INS and 1 intranasal antihistamine spray preparations conducted with the use of appropriate search terms, yielded an initial 121 articles, 29 of which were identified as appropriate for review and grading for quality of evidence. RESULTS: The analysis provided no definitive evidence regarding how best to instruct patients to use INS or antihistamine spray devices. CONCLUSIONS: On the basis of a lack of clear evidence regarding instructions to maximize efficacy and safety of these drugs, the panel recommended a 7-step standard technique.
OBJECTIVE: The effectiveness of topical intranasal steroids (INS) sprays for the treatment of allergic and nonallergic rhinitis may be limited by lack of instruction in the optimal spray technique. To determine whether the technique used affects the efficacy and safety of the product, this review of evidence had the goal of identifying and establishing a preferred method of applying INS sprays. STUDY DESIGN: A MEDLINE search of pertinent literature on 7 INS and 1 intranasal antihistamine spray preparations conducted with the use of appropriate search terms, yielded an initial 121 articles, 29 of which were identified as appropriate for review and grading for quality of evidence. RESULTS: The analysis provided no definitive evidence regarding how best to instruct patients to use INS or antihistamine spray devices. CONCLUSIONS: On the basis of a lack of clear evidence regarding instructions to maximize efficacy and safety of these drugs, the panel recommended a 7-step standard technique.
Authors: Jarrod A Keeler; Aniruddha Patki; Charles R Woodard; Dennis O Frank-Ito Journal: J Aerosol Med Pulm Drug Deliv Date: 2015-08-13 Impact factor: 2.849
Authors: Saangyoung E Lee; William C Brown; Mark W Gelpi; Adam J Kimple; Brent A Senior; Adam M Zanation; Brian D Thorp; Charles S Ebert Journal: Int Forum Allergy Rhinol Date: 2020-04-13 Impact factor: 3.858
Authors: Soner Akbaba; Hüseyin Köseoğlu; Bahadır Osman Bozkırlı; Fatma Ebru Akın; Rıza Haldun Gündoğdu; Osman Ersoy; Jale Karakaya; Pamir Eren Ersoy Journal: Int J Clin Exp Med Date: 2014-05-15