Literature DB >> 14717622

Comparative tolerability of sedative agents in head-injured adults.

Susan C Urwin1, David K Menon.   

Abstract

Sedative agents are widely used in the management of patients with head injury. These drugs can facilitate assisted ventilation and may provide useful reductions in cerebral oxygen demand. However, they may compromise cerebral oxygen delivery via their cardiovascular effects. In addition, individual sedative agents have specific and sometimes serious adverse effects. This review focuses on the different classes of sedative agents used in head injury, with a discussion of their role in the context of clinical pathophysiology. While there is no sedative that has all the desirable characteristics for an agent in this clinical setting, careful titration of dose, combination of agents, and a clear understanding of the pathophysiology and pharmacology of these agents will allow safe sedative administration in head injury.

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Year:  2004        PMID： 14717622     DOI： 10.2165/00002018-200427020-00003

Source DB:  PubMed          Journal:  Drug Saf        ISSN： 0114-5916            Impact factor:   5.606


  253 in total

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Journal:  Anesthesiology       Date:  1987-06       Impact factor: 7.892

3.  Propofol infusion for sedation of patients with head injury in intensive care. A preliminary report.

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Journal:  Anaesthesia       Date:  1989-03       Impact factor: 6.955

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Authors:  J E Brian; A B Seifen
Journal:  Anesth Analg       Date:  1987-05       Impact factor: 5.108

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Authors:  A ter Minassian; L Beydon; P Decq; F Bonnet
Journal:  Anesth Analg       Date:  1997-01       Impact factor: 5.108

6.  Auditory and electroencephalographic effects of midazolam and alpha-hydroxy-midazolam in healthy subjects.

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Journal:  Br J Clin Pharmacol       Date:  2000-01       Impact factor: 4.335

7.  Elevated pancreatic enzymes after extended propofol therapy.

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Journal:  Pharmacotherapy       Date:  1998 May-Jun       Impact factor: 4.705

8.  Altered gastric emptying in the head-injured patient: relationship to feeding intolerance.

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Journal:  J Neurosurg       Date:  1991-05       Impact factor: 5.115

9.  Reduction of stress/catecholamine-induced cardiac necrosis by beta 1-selective blockade.

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Journal:  Lancet       Date:  1987-09-12       Impact factor: 79.321

10.  Cerebrovascular and cerebral metabolic effects of physostigmine, midazolam, and a benzodiazepine antagonist.

Authors:  W E Hoffman; R F Albrecht; D J Miletich; T J Hagen; J M Cook
Journal:  Anesth Analg       Date:  1986-06       Impact factor: 5.108
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  10 in total

1.  Ketamine does not increase intracranial pressure compared with opioids: meta-analysis of randomized controlled trials.

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Journal:  J Anesth       Date:  2014-05-24       Impact factor: 2.078

Review 2.  The emerging use of ketamine for anesthesia and sedation in traumatic brain injuries.

Authors:  Lee C Chang; Sally R Raty; Jaime Ortiz; Neil S Bailard; Sanjay J Mathew
Journal:  CNS Neurosci Ther       Date:  2013-03-11       Impact factor: 5.243

3.  Effect of sedative agent selection on morbidity, mortality and length of stay in patients with increase in intracranial pressure.

Authors:  Brian G Cornelius; Elizabeth Webb; Angela Cornelius; Kenneth W G Smith; Srdan Ristic; Jay Jain; Urska Cvek; Marjan Trutschl
Journal:  World J Emerg Med       Date:  2018

4.  Sedation in traumatic brain injury.

Authors:  Oliver Flower; Simon Hellings
Journal:  Emerg Med Int       Date:  2012-09-20       Impact factor: 1.112

5.  Effect of Dezocine on Hemodynamic Indexes of Postoperative Patients With Traumatic Brain Injury (TBI)---A Pilot Study.

Authors:  Xuejian Wang; Yang Chen; Zhifeng Wang; Yi Zhang; Zhiming Cui; Chen Sun
Journal:  Front Pharmacol       Date:  2022-03-31       Impact factor: 5.810

Review 6.  Anesthetic management of unruptured intracranial aneurysms: a qualitative systematic review.

Authors:  Shooka Esmaeeli; Juan Valencia; Lauren K Buhl; Andres Brenes Bastos; Sogand Goudarzi; Matthias Eikermann; Corey Fehnel; Richard Pollard; Ajith Thomas; Christopher S Ogilvy; Shahzad Shaefi; Ala Nozari
Journal:  Neurosurg Rev       Date:  2021-01-07       Impact factor: 2.800

7.  Is jugular bulb oximetry monitoring associated with outcome in out of hospital cardiac arrest patients?

Authors:  Jaromir Richter; Peter Sklienka; Adarsh Eshappa Setra; Roman Zahorec; Samaresh Das; Nilay Chatterjee
Journal:  J Clin Monit Comput       Date:  2020-05-20       Impact factor: 2.502

8.  Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injury.

Authors:  Anne Sebastiani; Simone Bender; Michael K E Schäfer; Serge C Thal
Journal:  BMC Anesthesiol       Date:  2022-03-04       Impact factor: 2.217

9.  A One-Day Prospective National Observational Study on Sedation-Analgesia of Patients with Brain Injury in French Intensive Care Units: The SEDA-BIP-ICU (Sedation-Analgesia in Brain Injury Patient in ICU) Study.

Authors:  Simon Poignant; Bernard Vigué; Patricia Balram; Mathieu Biais; Romain Carillon; Vincent Cottenceau; Claire Dahyot-Fizelier; Vincent Degos; Thomas Geeraerts; Patrick Jeanjean; Emmanuel Vega; Sigismond Lasocki; Fabien Espitalier; Marc Laffon
Journal:  Neurocrit Care       Date:  2021-07-30       Impact factor: 3.210

Review 10.  Optimizing sedation in patients with acute brain injury.

Authors:  Mauro Oddo; Ilaria Alice Crippa; Sangeeta Mehta; David Menon; Jean-Francois Payen; Fabio Silvio Taccone; Giuseppe Citerio
Journal:  Crit Care       Date:  2016-05-05       Impact factor: 9.097
  10 in total

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