| Literature DB >> 14714651 |
Alexandre R Tumlinson1, Lida P Hariri, Urs Utzinger, Jennifer K Barton.
Abstract
We have designed a multimodality system that combines optical coherence tomography (OCT) and laser-induced fluorescence (LIF) in a 2.0-mm-diameter endoscopic package. OCT provides approximately 18-microm resolution cross-sectional structural information over a 6-mm field. LIF spectra are collected sequentially at submillimeter resolution across the same field and provide histochemical information about the tissue. We present the use of a rod prism to reduce the asymmetry in the OCT beam caused by a cylindrical window. The endoscope has been applied to investigate mouse colon cancer in vivo.Entities:
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Year: 2004 PMID: 14714651 DOI: 10.1364/ao.43.000113
Source DB: PubMed Journal: Appl Opt ISSN: 1559-128X Impact factor: 1.980