Literature DB >> 14711001

The anti-parasitic effects of nitric oxide.

Paolo Ascenzi1, Alessio Bocedi, Luigi Gradoni.   

Abstract

Endogenous and exogenous nitric oxide (NO) possesses antiparasitic effects on both Protozoa and Metazoa. However, NO production requires a tight control to limit cytotoxic damage to the host's own cells. The best known parasitic macromolecular targets for NO(-donors) are cysteine proteases, which are relevant in several aspects of the parasite life cycle and parasite-host relationships, and appear as promising targets for anti-parasitic chemotherapy.

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Year:  2003        PMID： 14711001     DOI： 10.1080/15216540310001639265

Source DB:  PubMed          Journal:  IUBMB Life        ISSN： 1521-6543            Impact factor:   3.885


  10 in total

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3.  The impact of l-arginine supplementation on the enteral phase of experimental Trichinella spiralis infection in treated and untreated mice.

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4.  Comparative study of nitric oxide (NO) production during human hydatidosis: relationship with cystic fluid fertility.

Authors:  Razika Zeghir-Bouteldja; Manel Amri; Samia Bouaziz; Dalila Mezioug; Chafia Touil-Boukoffa
Journal:  Parasitol Res       Date:  2012-11-17       Impact factor: 2.289

5.  In vitro and in vivo antiproliferative and trypanocidal activities of ruthenium NO donors.

Authors:  J J N Silva; A L Osakabe; W R Pavanelli; J S Silva; D W Franco
Journal:  Br J Pharmacol       Date:  2007-07-02       Impact factor: 8.739

6.  In vitro and in vivo efficacy of ether lipid edelfosine against Leishmania spp. and SbV-resistant parasites.

Authors:  Rubén E Varela-M; Janny A Villa-Pulgarin; Edward Yepes; Ingrid Müller; Manuel Modolell; Diana L Muñoz; Sara M Robledo; Carlos E Muskus; Julio López-Abán; Antonio Muro; Iván D Vélez; Faustino Mollinedo
Journal:  PLoS Negl Trop Dis       Date:  2012-04-10

7.  Optimization of the Timing of Induction for the Assessment of Nitric Oxide Production in Leishmania major Infected Macrophage Cells.

Authors:  Somaye Sadeghi; Negar Seyed; Sima Rafati; Tahereh Taheri
Journal:  Iran J Parasitol       Date:  2016 Jul-Sep       Impact factor: 1.012

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9.  Supplementation of host response by targeting nitric oxide to the macrophage cytosol is efficacious in the hamster model of visceral leishmaniasis and adds to efficacy of amphotericin B.

Authors:  Sanketkumar Pandya; Rahul Kumar Verma; Prashant Khare; Brajendra Tiwari; Dadi A Srinivasarao; Anuradha Dube; Neena Goyal; Amit Misra
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2016-01-14       Impact factor: 4.077

10.  Leishmania donovani-Induced Increase in Macrophage Bcl-2 Favors Parasite Survival.

Authors:  Rajeev Kumar Pandey; Sanjana Mehrotra; Smriti Sharma; Ramachandra Subbaraya Gudde; Shyam Sundar; Chandrima Shaha
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  10 in total

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