Literature DB >> 1470921

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2.

D L Vaux1, I L Weissman, S K Kim.   

Abstract

Programmed cell death is a physiological process that eliminates unwanted cells. The bcl-2 gene regulates programmed cell death in mammalian cells, but the way it functions is not known. Expression of the human bcl-2 gene in the nematode Caenorhabditis elegans reduced the number of programmed cell deaths, suggesting that the mechanism of programmed cell death controlled by bcl-2 in humans is the same as that in nematodes.

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Year:  1992        PMID： 1470921     DOI： 10.1126/science.1470921

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  88 in total

1.  The midblastula transition in Xenopus embryos activates multiple pathways to prevent apoptosis in response to DNA damage.

Authors:  C V Finkielstein; A L Lewellyn; J L Maller
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-30       Impact factor: 11.205

Review 2.  Role of Bcl-2 family proteins and caspases in the regulation of apoptosis.

Authors:  Mohammad Shamsul Ola; Mohd Nawaz; Haseeb Ahsan
Journal:  Mol Cell Biochem       Date:  2011-01-06       Impact factor: 3.396

3.  A sensitive near-infrared fluorescent probe for caspase-mediated apoptosis: Synthesis and application in cell imaging.

Authors:  Yepeng Luan; Qiuhong Yang; Yumei Xie; Shaofeng Duan; Shuang Cai; M L Forrest
Journal:  Drug Discov Ther       Date:  2011-01-01

Review 4.  Cancer models in Caenorhabditis elegans.

Authors:  Natalia V Kirienko; Kumaran Mani; David S Fay
Journal:  Dev Dyn       Date:  2010-05       Impact factor: 3.780

5.  Suppression of apoptosis in insect cells stably transfected with baculovirus p35: dominant interference by N-terminal sequences p35(1-76).

Authors:  J L Cartier; P A Hershberger; P D Friesen
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

6.  Bcl-2 protein expression during murine development.

Authors:  D V Novack; S J Korsmeyer
Journal:  Am J Pathol       Date:  1994-07       Impact factor: 4.307

7.  Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33.

Authors:  Brendan D Galvin; Saechin Kim; H Robert Horvitz
Journal:  Genetics       Date:  2008-05-05       Impact factor: 4.562

8.  Role of the Fas pathway in Pseudomonas aeruginosa keratitis.

Authors:  Zimei Zhou; Minhao Wu; Ronald P Barrett; Sharon A McClellan; Yunfan Zhang; Linda D Hazlett
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-12-17       Impact factor: 4.799

9.  Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.

Authors:  A G Uren; M Pakusch; C J Hawkins; K L Puls; D L Vaux
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-14       Impact factor: 11.205

10.  Binding of DNA oligonucleotides to sequences in the promoter of the human bc1-2 gene.

Authors:  W M Olivas; L J Maher
Journal:  Nucleic Acids Res       Date:  1996-05-01       Impact factor: 16.971
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