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Literature DB >> 14708011

Ageing, repetitive genomes and DNA damage.

Abstract

The mitochondrial production of reactive oxygen species is inversely proportional to longevity in animals. A key question now is, which molecules, among those that are oxidized, affect the lifespan of the organism most significantly?

Entities: Chemical

Mesh：

Substances：
Reactive Oxygen Species

Year: 2004 PMID： 14708011 DOI： 10.1038/nrm1281

Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN： 1471-0072 Impact factor: 94.444

Keyword Cloud
Cited

37 in total

Review 1. Oxidative stress in diabetic nephropathy.

Authors: N Kashihara; Y Haruna; V K Kondeti; Y S Kanwar
Journal: Curr Med Chem Date: 2010 Impact factor: 4.530

2. Unifying the DNA end-processing roles of the artemis nuclease: Ku-dependent artemis resection at blunt DNA ends.

Authors: Howard H Y Chang; Go Watanabe; Michael R Lieber
Journal: J Biol Chem Date: 2015-08-14 Impact factor: 5.157

Review 3. The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?

Authors: Hirokazu Fukui; Carlos T Moraes
Journal: Trends Neurosci Date: 2008-04-09 Impact factor: 13.837

4. p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice.

Authors: Yvonne Begus-Nahrmann; André Lechel; Anna C Obenauf; Kodandaramireddy Nalapareddy; Elvira Peit; Eva Hoffmann; Falk Schlaudraff; Birgit Liss; Peter Schirmacher; Hans Kestler; Esther Danenberg; Nick Barker; Hans Clevers; Michael R Speicher; K Lenhard Rudolph
Journal: Nat Genet Date: 2009-08-30 Impact factor: 38.330

Ageing, repetitive genomes and DNA damage.

Review 1. Oxidative stress in diabetic nephropathy.

2. Unifying the DNA end-processing roles of the artemis nuclease: Ku-dependent artemis resection at blunt DNA ends.

Review 3. The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?

4. p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice.

5. 8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress.

Review 6. Non-homologous DNA end joining and alternative pathways to double-strand break repair.

Review 7. Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humans.

8. Polymorphism within the distal RAD51 gene promoter is associated with colorectal cancer in a Polish population.

9. Comparison of nonhomologous end joining and homologous recombination in human cells.

10. DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells.