Literature DB >> 14706462

Target-selected mutagenesis of the rat.

Bart M G Smits1, Josine Mudde, Ronald H A Plasterk, Edwin Cuppen.   

Abstract

The rat is one of the most extensively studied model organisms, and with its genome being sequenced, tools to manipulate gene function in vivo have become increasingly important. We here report proof of principle for target-selected mutagenesis as a reverse genetic or knockout approach for the rat.

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Year:  2004        PMID： 14706462     DOI： 10.1016/j.ygeno.2003.08.010

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  23 in total

1.  Mismatch cleavage by single-strand specific nucleases.

Authors:  Bradley J Till; Chris Burtner; Luca Comai; Steven Henikoff
Journal:  Nucleic Acids Res       Date:  2004-05-11       Impact factor: 16.971

2.  Behavioural therapy based on distraction alleviates impaired fear extinction in male serotonin transporter knockout rats.

Authors:  Lourens J P Nonkes; Maaike de Pooter; Judith R Homberg
Journal:  J Psychiatry Neurosci       Date:  2012-07       Impact factor: 6.186

3.  Target-selected mutant screen by TILLING in Drosophila.

Authors:  Sylke Winkler; Anja Schwabedissen; Dana Backasch; Christian Bökel; Claudia Seidel; Stefanie Bönisch; Maximilian Fürthauer; Antje Kuhrs; Laura Cobreros; Michael Brand; Marcos González-Gaitán
Journal:  Genome Res       Date:  2005-05       Impact factor: 9.043

4.  Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics.

Authors:  Bart M G Smits; Theo A Peters; Joram D Mul; Huib J Croes; Jack A M Fransen; Andy J Beynon; Victor Guryev; Ronald H A Plasterk; Edwin Cuppen
Journal:  Genetics       Date:  2005-06-18       Impact factor: 4.562

5.  Retention of induced mutations in a Drosophila reverse-genetic resource.

Authors:  Jennifer L Cooper; Elizabeth A Greene; Bradley J Till; Christine A Codomo; Barbara T Wakimoto; Steven Henikoff
Journal:  Genetics       Date:  2008-09-09       Impact factor: 4.562

Review 6.  Zinc-finger nucleases: new strategies to target the rat genome.

Authors:  Aron M Geurts; Carol Moreno
Journal:  Clin Sci (Lond)       Date:  2010-07-06       Impact factor: 6.124

Review 7.  Transgenic modifications of the rat genome.

Authors:  Laurent Tesson; Jean Cozzi; Séverine Ménoret; Séverine Rémy; Claire Usal; Alexandre Fraichard; Ignacio Anegon
Journal:  Transgenic Res       Date:  2005-10       Impact factor: 2.788

8.  Genetic variation in coding regions between and within commonly used inbred rat strains.

Authors:  Bart M G Smits; Bert F M van Zutphen; Ronald H A Plasterk; Edwin Cuppen
Journal:  Genome Res       Date:  2004-07       Impact factor: 9.043

9.  TILLING in Lotus japonicus identified large allelic series for symbiosis genes and revealed a bias in functionally defective ethyl methanesulfonate alleles toward glycine replacements.

Authors:  Jillian Perry; Andreas Brachmann; Tracey Welham; Andreas Binder; Myriam Charpentier; Martin Groth; Kristina Haage; Katharina Markmann; Trevor L Wang; Martin Parniske
Journal:  Plant Physiol       Date:  2009-07-29       Impact factor: 8.340

10.  Acute tryptophan depletion dose dependently impairs object memory in serotonin transporter knockout rats.

Authors:  J D A Olivier; L A W Jans; G A H Korte-Bouws; S M Korte; P M T Deen; A R Cools; B A Ellenbroek; A Blokland
Journal:  Psychopharmacology (Berl)       Date:  2008-06-10       Impact factor: 4.530
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