CASE REPORT: We present a rare case of a gliosarcoma occurring 8 years following treatment for a medulloblastoma. The patient was diagnosed with a medulloblastoma at the age of 13 years. We considered the possibility of a radiation-induced tumour and present evidence supporting this view. The second cerebral tumour was excised and confirmed to be a gliosarcoma. The tumour bed was re-irradiated with three-dimensional conformal radiotherapy (3DCRT). She remained well for 6 months, after which there was clinicoradiological progression. CONCLUSIONS: During long-term follow-up of patients with medulloblastomas, the possibility of radiation-induced neoplasms must be borne in mind. Copyright 2003 Springer-Verlag
CASE REPORT: We present a rare case of a gliosarcoma occurring 8 years following treatment for a medulloblastoma. The patient was diagnosed with a medulloblastoma at the age of 13 years. We considered the possibility of a radiation-induced tumour and present evidence supporting this view. The second cerebral tumour was excised and confirmed to be a gliosarcoma. The tumour bed was re-irradiated with three-dimensional conformal radiotherapy (3DCRT). She remained well for 6 months, after which there was clinicoradiological progression. CONCLUSIONS: During long-term follow-up of patients with medulloblastomas, the possibility of radiation-induced neoplasms must be borne in mind. Copyright 2003 Springer-Verlag
Authors: A K Osumi; R E Mclendon; R D Tien; H S Friedman; M Graham; B Hockenberger; E C Halperin; W J Oakes Journal: Clin Neuropathol Date: 1994 Sep-Oct Impact factor: 1.368
Authors: T E Merchant; M H Wang; T Haida; K L Lindsley; J Finlay; I J Dunkel; M K Rosenblum; S A Leibel Journal: Int J Radiat Oncol Biol Phys Date: 1996-08-01 Impact factor: 7.038
Authors: Patrick Schuss; Christian T Ulrich; Patrick N Harter; Dominique S Tews; Volker Seifert; Kea Franz Journal: J Neurooncol Date: 2010-10-19 Impact factor: 4.130