Literature DB >> 14702390

The principal chloroquine resistance protein of Plasmodium falciparum is a member of the drug/metabolite transporter superfamily.

Can V Tran1, Milton H Saier.   

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Year:  2004        PMID： 14702390     DOI： 10.1099/mic.0.26818-0

Source DB:  PubMed          Journal:  Microbiology        ISSN： 1350-0872            Impact factor:   2.777


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  33 in total

1.  Mutations conferring drug resistance in malaria parasite drug transporters Pgh1 and PfCRT do not affect steady-state vacuolar Ca2+.

Authors:  Giancarlo A Biagini; David A Fidock; Patrick G Bray; Stephen A Ward
Journal:  Antimicrob Agents Chemother       Date:  2005-11       Impact factor: 5.191

2.  Mutations in pfmdr1 modulate the sensitivity of Plasmodium falciparum to the intrinsic antiplasmodial activity of verapamil.

Authors:  Rhys Hayward; Kevin J Saliba; Kiaran Kirk
Journal:  Antimicrob Agents Chemother       Date:  2005-02       Impact factor: 5.191

3.  Incorporation of an intramolecular hydrogen-bonding motif in the side chain of 4-aminoquinolines enhances activity against drug-resistant P. falciparum.

Authors:  Peter B Madrid; Ally P Liou; Joseph L DeRisi; R Kiplin Guy
Journal:  J Med Chem       Date:  2006-07-27       Impact factor: 7.446

Review 4.  Transporters involved in resistance to antimalarial drugs.

Authors:  Stephanie G Valderramos; David A Fidock
Journal:  Trends Pharmacol Sci       Date:  2006-09-25       Impact factor: 14.819

5.  Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum.

Authors:  Cecilia P Sanchez; Petra Rohrbach; Jeremy E McLean; David A Fidock; Wilfred D Stein; Michael Lanzer
Journal:  Mol Microbiol       Date:  2007-04       Impact factor: 3.501

6.  Chloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoforms.

Authors:  David C Reeves; David A Liebelt; Viswanathan Lakshmanan; Paul D Roepe; David A Fidock; Myles H Akabas
Journal:  Mol Biochem Parasitol       Date:  2006-09-25       Impact factor: 1.759

7.  Chloroquine resistance-conferring mutations in pfcrt give rise to a chloroquine-associated H+ leak from the malaria parasite's digestive vacuole.

Authors:  Adele M Lehane; Kiaran Kirk
Journal:  Antimicrob Agents Chemother       Date:  2008-10-13       Impact factor: 5.191

8.  Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.

Authors:  David J Johnson; David A Fidock; Mathirut Mungthin; Viswanathan Lakshmanan; Amar Bir Singh Sidhu; Patrick G Bray; Stephen A Ward
Journal:  Mol Cell       Date:  2004-09-24       Impact factor: 17.970

Review 9.  Drug-resistant malaria - an insight.

Authors:  John E Hyde
Journal:  FEBS J       Date:  2007-09       Impact factor: 5.542

10.  State-dependent block of Na+ channels by articaine via the local anesthetic receptor.

Authors:  Ging Kuo Wang; Joanna Calderon; Shiow-Jiin Jaw; Sho-Ya Wang
Journal:  J Membr Biol       Date:  2009-05-06       Impact factor: 1.843
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