Literature DB >> 14698239

Express analysis of explosives, chemical warfare agents and drugs with multicapillary column gas chromatography and ion mobility increment spectrometry.

Igor A Buryakov1.   

Abstract

Description of a gas chromatograph designed for express analysis of explosives (2,4-dinitrotoluene, 2,4,6-trinitrotoluene, pentaerythritol tetranitrate), chemical warfare agents (mustard gas, lewisite, sarin) and drugs (heroin, cocaine hydrochloride, crack) is given. The devices comprises a multicapillary chromatographic column and an ion mobility increment spectrometer (MCC-IMIS). The main analytical characteristics of an IMIS (estimated detection limit (DL), linear dynamic range (LDR), speed of response) and a chromatographic column (separation power, degree of separation, a number of possible peaks at a chromatogram section, divided by analysis time) are determined. The maximum value of DL equal to 5 pg/ml was registered for cis-alpha-LW, and the lowest one of 0.001 pg/ml was for cocaine. The maximum value of LDR equal to 1000 was registered for sarin and the lowest one of 150 was for the ions of lewisite. Speed of response of one compound detection with the IMIS was 0.7 s.

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Year:  2004        PMID: 14698239     DOI: 10.1016/j.jchromb.2003.10.064

Source DB:  PubMed          Journal:  J Chromatogr B Analyt Technol Biomed Life Sci        ISSN: 1570-0232            Impact factor:   3.205


  7 in total

1.  A high voltage asymmetric waveform generator for FAIMS.

Authors:  Jesse D Canterbury; James Gladden; Lon Buck; Roy Olund; Michael J MacCoss
Journal:  J Am Soc Mass Spectrom       Date:  2010-02-18       Impact factor: 3.109

2.  Optimization of the design and operation of FAIMS analyzers.

Authors:  Alexandre A Shvartsburg; Keqi Tang; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2005-01       Impact factor: 3.109

3.  FAIMS operation for realistic gas flow profile and asymmetric waveforms including electronic noise and ripple.

Authors:  Alexandre A Shvartsburg; Keqi Tang; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2005-09       Impact factor: 3.109

4.  High-resolution field asymmetric waveform ion mobility spectrometry using new planar geometry analyzers.

Authors:  Alexandre A Shvartsburg; Fumin Li; Keqi Tang; Richard D Smith
Journal:  Anal Chem       Date:  2006-06-01       Impact factor: 6.986

5.  Scaling of the resolving power and sensitivity for planar FAIMS and mobility-based discrimination in flow- and field-driven analyzers.

Authors:  Alexandre A Shvartsburg; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2007-06-30       Impact factor: 3.109

6.  Optimum waveforms for differential ion mobility spectrometry (FAIMS).

Authors:  Alexandre A Shvartsburg; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2008-05-16       Impact factor: 3.109

Review 7.  Recommendations for reporting ion mobility Mass Spectrometry measurements.

Authors:  Valérie Gabelica; Alexandre A Shvartsburg; Carlos Afonso; Perdita Barran; Justin L P Benesch; Christian Bleiholder; Michael T Bowers; Aivett Bilbao; Matthew F Bush; J Larry Campbell; Iain D G Campuzano; Tim Causon; Brian H Clowers; Colin S Creaser; Edwin De Pauw; Johann Far; Francisco Fernandez-Lima; John C Fjeldsted; Kevin Giles; Michael Groessl; Christopher J Hogan; Stephan Hann; Hugh I Kim; Ruwan T Kurulugama; Jody C May; John A McLean; Kevin Pagel; Keith Richardson; Mark E Ridgeway; Frédéric Rosu; Frank Sobott; Konstantinos Thalassinos; Stephen J Valentine; Thomas Wyttenbach
Journal:  Mass Spectrom Rev       Date:  2019-02-01       Impact factor: 10.946

  7 in total

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