Literature DB >> 14696673

Prevention of experimentally-induced gastric ulcers in rats by an ethanolic extract of "Parsley" Petroselinum crispum.

Tawfeq Al-Howiriny1, Mohammed Al-Sohaibani, Kamal El-Tahir, Syed Rafatullah.   

Abstract

An ethanolic extract of Parsley, Petroselinum crispum (Mill.) Nym.ex A.W. Hill (Umbelliferae), was tested for its ability to inhibit gastric secretion and to protect gastric mucosa against the injuries caused by pyloric ligation, hypothermic restraint stress, indomethacin and cytodestructive agents (80% ethanol, 0.2 M NaOH and 25% NaCl) in rats. The extract in doses of 1 and 2 g/kg body weight had a significant antiulcerogenic activity on the models used. Besides, ethanol-induced depleted gastric wall mucus and non-protein sulfhydryl contents were replenished by pretreatment with Parsley extract. Acute toxicity tests showed a large margin of safety for the extract. The phytochemical screening of Parsley leaves revealed the presence of tannins, flavonoids, sterols and/or triterpenes.

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Year:  2003        PMID： 14696673     DOI： 10.1142/S0192415X03001405

Source DB:  PubMed          Journal:  Am J Chin Med        ISSN： 0192-415X            Impact factor:   4.667


  9 in total

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2.  Beneficial effects of Foeniculum vulgare on ethanol-induced acute gastric mucosal injury in rats.

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3.  Anti-ulcerogenic activity of the methanol root bark extract of Cochlospermum planchonii (Hook f).

Authors:  Maxwell I Ezeja; Aruh O Anaga
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4.  The effect of hydroalcoholic extract of P. crispum on sperm parameters, testis tissue and serum nitric oxide levels in mice.

Authors:  Cyrus Jalili; Mohammad Reza Salahshoor; Tahere Naderi
Journal:  Adv Biomed Res       Date:  2015-02-11

5.  Protective effect of Petroselinum crispum extract in abortion using prostadin-induced renal dysfunction in female rats.

Authors:  Maryam Rezazad; Farah Farokhi
Journal:  Avicenna J Phytomed       Date:  2014-09

6.  Protective effects of Mentha piperita L. leaf essential oil against CCl4 induced hepatic oxidative damage and renal failure in rats.

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Journal:  Lipids Health Dis       Date:  2018-01-09       Impact factor: 3.876

Review 7.  ANTI-ULCEROGENIC EFFICACY AND MECHANISMS OF EDIBLE AND NATURAL INGREDIENTS IN NSAID-INDUCED ANIMAL MODELS.

Authors:  Weiping Bi; Lizhi Hu; Mao-Qiang Man
Journal:  Afr J Tradit Complement Altern Med       Date:  2017-06-05

8.  Petroselinum Crispum is Effective in Reducing Stress-Induced Gastric Oxidative Damage.

Authors:  Ayşin Akıncı; Mukaddes Eşrefoğlu; Elif Taşlıdere; Burhan Ateş
Journal:  Balkan Med J       Date:  2017-01-05       Impact factor: 2.021

9.  Phytochemical Screening, In Vitro and In Silico Studies of Volatile Compounds from Petroselinum crispum (Mill) Leaves Grown in Saudi Arabia.

Authors:  Ahmed I Foudah; Mohammad H Alqarni; Aftab Alam; Mohammad Ayman Salkini; Samir A Ross; Hasan S Yusufoglu
Journal:  Molecules       Date:  2022-01-29       Impact factor: 4.411
  9 in total

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