Literature DB >> 14694250

Time course of changes in driving simulator performance with and without treatment in patients with sleep apnoea hypopnoea syndrome.

P M Turkington1, M Sircar, D Saralaya, M W Elliott.   

Abstract

BACKGROUND: Improvements in driving simulator performance have been demonstrated in patients with sleep apnoea hypopnoea syndrome (SAHS) after several months of treatment, but it is not known how quickly these improvements are achieved and lost. The aim of this study was to assess the time course of changes in driving simulator performance in patients with SAHS following treatment with continuous positive airways pressure (CPAP).
METHODS: Eighteen patients with severe SAHS performed a driving simulator test at baseline (before treatment) and at days 1, 3, and 7 of a 2 week CPAP trial period. CPAP was then discontinued and the patients performed three further driving simulator tests after 1, 3, and 7 days. Eighteen patients with severe SAHS acted as controls and performed the driving simulator test on seven occasions in a pattern similar to that of the treated patients.
RESULTS: Significant improvements in tracking error (p=0.004), reaction time (p=0.036), and the number of off road events per hour (p=0.032) were seen in the CPAP treated group compared with the controls at 7 days. Following discontinuation of CPAP for 7 days a significant difference in driving simulator performance persisted between the two groups, but the size of the difference had reduced.
CONCLUSION: Driving simulator performance in patients with severe SAHS improves within the first few days of starting CPAP and these improvements appear to be sustained for up to 1 week after withdrawal. Further data about the usefulness of driving simulators in predicting safe driving are needed before these results can be used in advising patients on driving. However, the data appear to suggest that driving can be safely resumed after a few days of effective CPAP treatment.

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Year:  2004        PMID: 14694250      PMCID: PMC1758840     

Source DB:  PubMed          Journal:  Thorax        ISSN: 0040-6376            Impact factor:   9.139


  31 in total

1.  Systematic review and meta-analysis of the literature regarding the diagnosis of sleep apnea.

Authors:  S D Ross; I A Sheinhait; K J Harrison; M Kvasz; J E Connelly; S A Shea; I E Allen
Journal:  Sleep       Date:  2000-06-15       Impact factor: 5.849

2.  Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP.

Authors:  C F George
Journal:  Thorax       Date:  2001-07       Impact factor: 9.139

3.  Driving simulator performance in patients with sleep apnea.

Authors:  L J Findley; M J Fabrizio; H Knight; B B Norcross; A J LaForte; P M Suratt
Journal:  Am Rev Respir Dis       Date:  1989-08

4.  Automobile accidents involving patients with obstructive sleep apnea.

Authors:  L J Findley; M E Unverzagt; P M Suratt
Journal:  Am Rev Respir Dis       Date:  1988-08

5.  Treatment with nasal CPAP decreases automobile accidents in patients with sleep apnea.

Authors:  L Findley; C Smith; J Hooper; M Dineen; P M Suratt
Journal:  Am J Respir Crit Care Med       Date:  2000-03       Impact factor: 21.405

6.  Relationship between obstructive sleep apnoea, driving simulator performance, and risk of road traffic accidents.

Authors:  P M Turkington; M Sircar; V Allgar; M W Elliott
Journal:  Thorax       Date:  2001-10       Impact factor: 9.139

7.  Randomised prospective parallel trial of therapeutic versus subtherapeutic nasal continuous positive airway pressure on simulated steering performance in patients with obstructive sleep apnoea.

Authors:  M Hack; R J Davies; R Mullins; S J Choi; S Ramdassingh-Dow; C Jenkinson; J R Stradling
Journal:  Thorax       Date:  2000-03       Impact factor: 9.139

8.  Driving simulation with EEG monitoring in normal and obstructive sleep apnea patients.

Authors:  M R Risser; J C Ware; F G Freeman
Journal:  Sleep       Date:  2000-05-01       Impact factor: 5.849

9.  Sleepiness-related accidents in sleep apnea patients.

Authors:  S Horstmann; C W Hess; C Bassetti; M Gugger; J Mathis
Journal:  Sleep       Date:  2000-05-01       Impact factor: 5.849

10.  Steering simulation performance in patients with obstructive sleep apnoea and matched control subjects.

Authors:  M Juniper; M A Hack; C F George; R J Davies; J R Stradling
Journal:  Eur Respir J       Date:  2000-03       Impact factor: 16.671

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  20 in total

Review 1.  Continuous positive airway pressure reduces risk of motor vehicle crash among drivers with obstructive sleep apnea: systematic review and meta-analysis.

Authors:  Stephen Tregear; James Reston; Karen Schoelles; Barbara Phillips
Journal:  Sleep       Date:  2010-10       Impact factor: 5.849

2.  Relationship Between Obesity and Driving.

Authors:  Gary G Kay; David McLaughlin
Journal:  Curr Obes Rep       Date:  2014-09

3.  Novice drivers' performance after different alcohol dosages and placebo in the divided-attention steering simulator (DASS).

Authors:  Joris C Verster; Anne E Wester; Maartje Goorden; Jan-Peter van Wieringen; Berend Olivier; Edmund R Volkerts
Journal:  Psychopharmacology (Berl)       Date:  2009-01-06       Impact factor: 4.530

4.  Driving simulator performance remains impaired in patients with severe OSA after CPAP treatment.

Authors:  Andrew Vakulin; Stuart D Baulk; Peter G Catcheside; Nick A Antic; Cameron J van den Heuvel; Jillian Dorrian; R Doug McEvoy
Journal:  J Clin Sleep Med       Date:  2011-06-15       Impact factor: 4.062

Review 5.  Physiological consequences of CPAP therapy withdrawal in patients with obstructive sleep apnoea-an opportunity for an efficient experimental model.

Authors:  Esther I Schwarz; John R Stradling; Malcolm Kohler
Journal:  J Thorac Dis       Date:  2018-01       Impact factor: 2.895

6.  DRIVING PERFORMANCE AND DRIVER STATE IN OBSTRUCTIVE SLEEP APNEA: WHAT CHANGES WITH POSITIVE AIRWAY PRESSURE?

Authors:  Nazan Aksan; Robert Marini; Jon Tippin; Jeffrey Dawson; Matthew Rizzo
Journal:  Proc Int Driv Symp Hum Factors Driv Assess Train Veh Des       Date:  2017

Review 7.  CPAP washout prior to reevaluation polysomnography: a sleep surgeon's perspective.

Authors:  Anneclaire V M T Vroegop; Jim W Smithuis; Linda B L Benoist; Olivier M Vanderveken; Nico de Vries
Journal:  Sleep Breath       Date:  2014-12-09       Impact factor: 2.816

8.  EFFECTS OF FATIGUE ON REAL-WORLD DRIVING IN DISEASED AND CONTROL PARTICIPANTS.

Authors:  Nazan Aksan; Jeffrey Dawson; Jon Tippin; John D Lee; Matthew Rizzo
Journal:  Proc Int Driv Symp Hum Factors Driv Assess Train Veh Des       Date:  2015-06

9.  Patient education combined in a music and habit-forming intervention for adherence to continuous positive airway (CPAP) prescribed for sleep apnea.

Authors:  Carol E Smith; Emily Dauz; Faye Clements; Marilyn Werkowitch; Robert Whitman
Journal:  Patient Educ Couns       Date:  2008-09-30

10.  Effects of armodafinil on simulated driving and self-report measures in obstructive sleep apnea patients prior to treatment with continuous positive airway pressure.

Authors:  Gary G Kay; Neil Feldman
Journal:  J Clin Sleep Med       Date:  2013-05-15       Impact factor: 4.062

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