Literature DB >> 11413347

Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP.

C F George1.   

Abstract

BACKGROUND: Patients with untreated obstructive sleep apnoea (OSA) have increased motor vehicle collisions (MVCs). When successfully treated, they report improved driving and fewer mishaps, but there are few objective data to confirm this. A study was therefore undertaken to examine actual MVC data in a large group of patients with OSA before and after treatment with continuous positive airway pressure (CPAP) compared with a control group matched for age, sex, and type of driver's licence (commercial or non-commercial).
METHODS: Two hundred and ten patients of mean (SD) age 52 (11) years, body mass index (BMI) 35.5 (10) kg/m(2), apnoea/hypopnoea index (AHI) 54 (29) events/h were treated with CPAP for at least 3 years. MVC records were obtained from the Ontario Ministry of Transportation (MTO) database for patients and an equal number of randomly selected control drivers. MVC rates were compared for 3 years before and after CPAP therapy for patients and for the corresponding time frames for controls.
RESULTS: Untreated patients with OSA had more MVCs than controls (mean (SD) MVCs/driver/year 0.18 (0.29) v 0.06 (0.17), p<0.001). Following CPAP treatment the number of MVCs/driver/year fell to normal (0.06 (0.17)) while, in controls, the MVC rate was unchanged over time (0.06 (0.17) v 0.07 (0.18), p=NS). Thus, the change in MVCs over time between the groups was very significant (change = -0.12 (95% CI -0.17 to -0.06), p<0.001)). The MVC rate in untreated patients (n=27) remained high over time. Driving exposure was not different following CPAP.
CONCLUSIONS: The risk of MVCs due to OSA is removed when patients are treated with CPAP. As such, any restrictions on driving because of OSA could be safely removed after treatment.

Entities:  

Mesh:

Year:  2001        PMID: 11413347      PMCID: PMC1746094          DOI: 10.1136/thorax.56.7.508

Source DB:  PubMed          Journal:  Thorax        ISSN: 0040-6376            Impact factor:   9.139


  19 in total

1.  Sleep apnea & automobile crashes.

Authors:  C F George; A Smiley
Journal:  Sleep       Date:  1999-09-15       Impact factor: 5.849

2.  Sleep apnoea patients have more automobile accidents.

Authors:  C F George; P W Nickerson; P J Hanly; T W Millar; M H Kryger
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3.  Automobile accidents involving patients with obstructive sleep apnea.

Authors:  L J Findley; M E Unverzagt; P M Suratt
Journal:  Am Rev Respir Dis       Date:  1988-08

Review 4.  Simulated long-term driving performance before and after uvulopalatopharyngoplasty.

Authors:  P O Haraldsson; C Carenfelt; H E Persson; C Sachs; J Törnros
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  1991       Impact factor: 1.538

5.  Treatment with nasal CPAP decreases automobile accidents in patients with sleep apnea.

Authors:  L Findley; C Smith; J Hooper; M Dineen; P M Suratt
Journal:  Am J Respir Crit Care Med       Date:  2000-03       Impact factor: 21.405

6.  Randomised prospective parallel trial of therapeutic versus subtherapeutic nasal continuous positive airway pressure on simulated steering performance in patients with obstructive sleep apnoea.

Authors:  M Hack; R J Davies; R Mullins; S J Choi; S Ramdassingh-Dow; C Jenkinson; J R Stradling
Journal:  Thorax       Date:  2000-03       Impact factor: 9.139

7.  Automobile accidents in patients with sleep disorders.

Authors:  M S Aldrich
Journal:  Sleep       Date:  1989-12       Impact factor: 5.849

8.  Long-term effect of uvulopalatopharyngoplasty on driving performance.

Authors:  P O Haraldsson; C Carenfelt; M Lysdahl; J Törnros
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1995-01

9.  [Traffic accidents in obstructive sleep apnea patients and effect of nasal CPAP treatment].

Authors:  H Minemura; T Akashiba; H Yamamoto; R Suzuki; D Itoh; K Kurashina; T Yoshizawa; T Horie
Journal:  Nihon Kyobu Shikkan Gakkai Zasshi       Date:  1993-09

10.  Clinical symptoms of sleep apnea syndrome and automobile accidents.

Authors:  P O Haraldsson; C Carenfelt; F Diderichsen; A Nygren; C Tingvall
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  1990       Impact factor: 1.538

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  88 in total

1.  Time course of changes in driving simulator performance with and without treatment in patients with sleep apnoea hypopnoea syndrome.

Authors:  P M Turkington; M Sircar; D Saralaya; M W Elliott
Journal:  Thorax       Date:  2004-01       Impact factor: 9.139

Review 2.  Continuous positive airway pressure reduces risk of motor vehicle crash among drivers with obstructive sleep apnea: systematic review and meta-analysis.

Authors:  Stephen Tregear; James Reston; Karen Schoelles; Barbara Phillips
Journal:  Sleep       Date:  2010-10       Impact factor: 5.849

3.  Sleep apnoea: a major and under-recognised public health concern.

Authors:  Walter T McNicholas; Yuanming Luo; Nanshan Zhong
Journal:  J Thorac Dis       Date:  2015-08       Impact factor: 2.895

Review 4.  Sleep.7: positive airway pressure therapy for obstructive sleep apnoea/hypopnoea syndrome.

Authors:  P Gordon; M H Sanders
Journal:  Thorax       Date:  2005-01       Impact factor: 9.139

Review 5.  The economic impact of obstructive sleep apnea.

Authors:  Nayef AlGhanim; Vikram R Comondore; John Fleetham; Carlo A Marra; Najib T Ayas
Journal:  Lung       Date:  2007-12-08       Impact factor: 2.584

6.  [Recommendations for ambulatory polygraphy by the Austrian Pneumology Society].

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Journal:  Wien Klin Wochenschr       Date:  2007       Impact factor: 1.704

7.  All APAPs Are Not Equivalent for the Treatment of Sleep Disordered Breathing: A Bench Evaluation of Eleven Commercially Available Devices.

Authors:  Kaixian Zhu; Gabriel Roisman; Sami Aouf; Pierre Escourrou
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8.  Correlates of a prescription for Bilevel positive airway pressure for treatment of obstructive sleep apnea among veterans.

Authors:  Skai W Schwartz; Julie Rosas; Michelle R Iannacone; Philip R Foulis; W McDowell Anderson
Journal:  J Clin Sleep Med       Date:  2013-04-15       Impact factor: 4.062

9.  Mandibular advancement splint as short-term alternative treatment in patients with obstructive sleep apnea already effectively treated with continuous positive airway pressure.

Authors:  Fernanda R Almeida; Alan Mulgrew; Najib Ayas; Hiroko Tsuda; Alan A Lowe; Nurit Fox; Sandra Harrison; John A Fleetham
Journal:  J Clin Sleep Med       Date:  2013-04-15       Impact factor: 4.062

Review 10.  Sleep. 5: Driving and automobile crashes in patients with obstructive sleep apnoea/hypopnoea syndrome.

Authors:  C F P George
Journal:  Thorax       Date:  2004-09       Impact factor: 9.139

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