PURPOSE: To evaluate the most effective parameters of Orbscan Corneal Topography System for subclinical keratoconus screening. METHODS: The study includes corneas from patients with clinical diagnosis of keratoconus (group 1, n=35), patients with subclinical keratoconus (group 2, n=14) and a control group of myopic subjects paired in gender, age and refractive spherical equivalent (group 3, n=35). Placement of the apex, anterior and posterior corneal elevation, minimal corneal thickness, anterior chamber depth and corneal diameter were evaluated. RESULTS: The most frequent location of the apex was at the inferotemporal sector (53%). Mean anterior elevation was 56.73 S.D. 25.95 mm in group 1 and 20.35 S.D. 8.04 mm in group 2; results that are statistically significant different from the control group (p<0.001). Mean posterior elevation was 126.23 S.D. 57.7 mm in group 1 and 54.28 S.D. 19.55 mm in group 2, both showing a statistically significant difference from the control group (p<0.001). Minimal corneal thickness and anterior chamber depth also showed statistically significant differences between the three groups. No differences were found in corneal diameter values. CONCLUSIONS: Statistically significant differences were found in anterior and posterior elevation, minimal corneal thickness and anterior chamber depth parameters, as measured by the Orbscan system, between normal myopic subjects and those with clinical and sub-clinical keratoconus. These parameters should be considered in the detection of patients with increased risk for developing secondary keratectasia following corneal refractive surgery.
PURPOSE: To evaluate the most effective parameters of Orbscan Corneal Topography System for subclinical keratoconus screening. METHODS: The study includes corneas from patients with clinical diagnosis of keratoconus (group 1, n=35), patients with subclinical keratoconus (group 2, n=14) and a control group of myopic subjects paired in gender, age and refractive spherical equivalent (group 3, n=35). Placement of the apex, anterior and posterior corneal elevation, minimal corneal thickness, anterior chamber depth and corneal diameter were evaluated. RESULTS: The most frequent location of the apex was at the inferotemporal sector (53%). Mean anterior elevation was 56.73 S.D. 25.95 mm in group 1 and 20.35 S.D. 8.04 mm in group 2; results that are statistically significant different from the control group (p<0.001). Mean posterior elevation was 126.23 S.D. 57.7 mm in group 1 and 54.28 S.D. 19.55 mm in group 2, both showing a statistically significant difference from the control group (p<0.001). Minimal corneal thickness and anterior chamber depth also showed statistically significant differences between the three groups. No differences were found in corneal diameter values. CONCLUSIONS: Statistically significant differences were found in anterior and posterior elevation, minimal corneal thickness and anterior chamber depth parameters, as measured by the Orbscan system, between normal myopic subjects and those with clinical and sub-clinical keratoconus. These parameters should be considered in the detection of patients with increased risk for developing secondary keratectasia following corneal refractive surgery.
Authors: Jason D Marsack; Jos J Rozema; Carina Koppen; Marie-Jose Tassignon; Raymond A Applegate Journal: Optom Vis Sci Date: 2013-04 Impact factor: 1.973
Authors: Uğur Tunç; Yusuf Berk Akbaş; Yusuf Yıldırım; Burçin Kepez Yıldız; Ahmet Kırgız; Ahmet Demirok Journal: Eye (Lond) Date: 2020-10-26 Impact factor: 4.456