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Literature DB >> 1468573

Human urokinase contains GalNAc beta (1-4)[Fuc alpha (1-3)]GlcNAc beta (1-2) as a novel terminal element in N-linked carbohydrate chains.

A A Bergwerff¹, J E Thomas-Oates, J van Oostrum, J P Kamerling, J F Vliegenthart.

Abstract

Structural analysis of enzymically released N-linked carbohydrate chains of human urokinase (urinary-type plasminogen activator) by 1H NMR spectroscopy and FAB-MS demonstrated that the N-linked oligosaccharides on the only N-glycosylation site contain diantennary structures with the novel GalNAc beta (1-4) [Fuc alpha (1-3)]GlcNAc beta (1-2) element in the upper or the lower branch.

Entities: Chemical Gene Species

Mesh：

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Year: 1992 PMID： 1468573 DOI： 10.1016/0014-5793(92)81512-k

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

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Cited

8 in total

1. Novel induction of alpha-lactalbumin-mediated lacdiNAc-R expression in vivo.

Authors: S I Do; K Y Lee; H N Kim
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Review 2. Schistosome glycoconjugates in host-parasite interplay.

Authors: C H Hokke; A M Deelder
Journal: Glycoconj J Date: 2001-08 Impact factor: 2.916

3. Fractionation and characterization of boar seminal plasma spermadhesion PSP-II glycoforms reveal the presence of uncommon N-acetylgalactosamine-containing N-linked oligosaccharides.

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Journal: Glycoconj J Date: 1997-02 Impact factor: 2.916

4. Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans.

Authors: Léa Chuzel; Samantha L Fossa; Madison L Boisvert; Samanta Cajic; René Hennig; Mehul B Ganatra; Udo Reichl; Erdmann Rapp; Christopher H Taron
Journal: Microb Cell Fact Date: 2021-08-21 Impact factor: 5.328

5. Glycomic Analysis of Life Stages of the Human Parasite Schistosoma mansoni Reveals Developmental Expression Profiles of Functional and Antigenic Glycan Motifs.

Authors: Cornelis H Smit; Angela van Diepen; D Linh Nguyen; Manfred Wuhrer; Karl F Hoffmann; André M Deelder; Cornelis H Hokke
Journal: Mol Cell Proteomics Date: 2015-04-16 Impact factor: 5.911

Human urokinase contains GalNAc beta (1-4)[Fuc alpha (1-3)]GlcNAc beta (1-2) as a novel terminal element in N-linked carbohydrate chains.

1. Novel induction of alpha-lactalbumin-mediated lacdiNAc-R expression in vivo.

Review 2. Schistosome glycoconjugates in host-parasite interplay.

3. Fractionation and characterization of boar seminal plasma spermadhesion PSP-II glycoforms reveal the presence of uncommon N-acetylgalactosamine-containing N-linked oligosaccharides.

4. Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans.

5. Glycomic Analysis of Life Stages of the Human Parasite Schistosoma mansoni Reveals Developmental Expression Profiles of Functional and Antigenic Glycan Motifs.

Review 6. Deciphering the glycogenome of schistosomes.

Review 7. The complexity of glycoprotein-derived glycans.

8. Towards Mapping of the Human Brain N-Glycome with Standardized Graphitic Carbon Chromatography.