Literature DB >> 14685314

Directed evolution of enzymes: new biocatalysts for asymmetric synthesis.

Marina Alexeeva1, Reuben Carr, Nicholas J Turner.   

Abstract

Directed evolution has been employed to generate new enzymes for the deracemisation of chiral amines.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 14685314     DOI： 10.1039/b311055a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  6 in total

Review 1.  Directed evolution drives the next generation of biocatalysts.

Authors:  Nicholas J Turner
Journal:  Nat Chem Biol       Date:  2009-08       Impact factor: 15.040

2.  A thermostable β-glucuronidase obtained by directed evolution as a reporter gene in transgenic plants.

Authors:  Ai-Sheng Xiong; Ri-He Peng; Jing Zhuang; Jian-Min Chen; Bin Zhang; Jian Zhang; Quan-Hong Yao
Journal:  PLoS One       Date:  2011-11-09       Impact factor: 3.240

3.  GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries.

Authors:  Andrew Currin; Jane Kwok; Joanna C Sadler; Elizabeth L Bell; Neil Swainston; Maria Ababi; Philip Day; Nicholas J Turner; Douglas B Kell
Journal:  ACS Synth Biol       Date:  2019-06-07       Impact factor: 5.110

4.  SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution.

Authors:  Andrew Currin; Neil Swainston; Philip J Day; Douglas B Kell
Journal:  Protein Eng Des Sel       Date:  2014-08-09       Impact factor: 1.650

Review 5.  Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.

Authors:  Andrew Currin; Neil Swainston; Philip J Day; Douglas B Kell
Journal:  Chem Soc Rev       Date:  2015-03-07       Impact factor: 54.564

6.  New recombinant cyclohexylamine oxidase variants for deracemization of secondary amines by orthogonally assaying designed mutants with structurally diverse substrates.

Authors:  Guangyue Li; Peiyuan Yao; Peiqian Cong; Jie Ren; Lei Wang; Jinhui Feng; Peter C K Lau; Qiaqing Wu; Dunming Zhu
Journal:  Sci Rep       Date:  2016-05-03       Impact factor: 4.379
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.