Literature DB >> 14682755

Concise and efficient synthesis of 4-fluoro-1H-pyrrolo[2,3-b]pyridine.

Carl Thibault1, Alexandre L'Heureux, Rajeev S Bhide, Réjean Ruel.   

Abstract

Two routes describing the preparation of 4-fluoro-1H-pyrrolo[2,3-b]pyridine (4a) from 1H-pyrrolo[2,3-b]pyridine N-oxide (1) are presented. Regioselective fluorination was achieved using either the Balz-Schiemann reaction or lithium-halogen exchange. [reaction: see text]

Entities:  

Year:  2003        PMID： 14682755     DOI： 10.1021/ol036030z

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Palladium-catalyzed amination of unprotected halo-7-azaindoles.

Authors:  Jaclyn L Henderson; Sarah M McDermott; Stephen L Buchwald
Journal:  Org Lett       Date:  2010-10-15       Impact factor: 6.005

Review 2.  Biaryl phosphane ligands in palladium-catalyzed amination.

Authors:  David S Surry; Stephen L Buchwald
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

3.  Palladium-catalyzed C-N and C-O bond formation of N-substituted 4-bromo-7-azaindoles with amides, amines, amino acid esters and phenols.

Authors:  Rajendra Surasani; Dipak Kalita; A V Dhanunjaya Rao; K B Chandrasekhar
Journal:  Beilstein J Org Chem       Date:  2012-11-19       Impact factor: 2.883
  3 in total

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