Literature DB >> 14672453

Influence of dexamethasone on some cellular aspects of the immune system in cats.

M Hoffmann-Jagielska1, A Winnicka, D Jagielski, R Lechowski.   

Abstract

In view of the frequent use of glucocorticoids in the treatment of cats, we studied the effect of dexamethasone on their immunological system. The phagocytic activity and oxidative burst of neutrophils and monocytes were evaluated by cytometric analysis using commercial kits and the subpopulations of lymphocytes were assessed. Neutrophilia and monocytosis reduced phagocytic activity, as shown from the number of phagocytized bacteria, and variations in the intensity of the oxidative burst in activated neutrophils and monocytes were observed. Dexamethasone also caused an increase in the number of B lymphocytes.

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Year:  2003        PMID: 14672453     DOI: 10.1023/a:1027376530463

Source DB:  PubMed          Journal:  Vet Res Commun        ISSN: 0165-7380            Impact factor:   2.459


  23 in total

Review 1.  The influence of corticosteroids on host defense mechanisms.

Authors:  L A Cohn
Journal:  J Vet Intern Med       Date:  1991 Mar-Apr       Impact factor: 3.333

2.  Plasma cell stomatitis-pharyngitis in cats: 40 cases (1973-1991).

Authors:  S D White; R A Rosychuk; T A Janik; P Denerolle; P Schultheiss
Journal:  J Am Vet Med Assoc       Date:  1992-05-01       Impact factor: 1.936

Review 3.  Ophthalmic emergencies.

Authors:  D C Mandell
Journal:  Clin Tech Small Anim Pract       Date:  2000-05

Review 4.  Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation.

Authors:  N J Goulding; H S Euzger; S K Butt; M Perretti
Journal:  Inflamm Res       Date:  1998-10       Impact factor: 4.575

Review 5.  Glucocorticosteroids as immunosuppressive agents.

Authors:  L A Cohn
Journal:  Semin Vet Med Surg (Small Anim)       Date:  1997-08

Review 6.  Control of ocular inflammation.

Authors:  D A Wilkie
Journal:  Vet Clin North Am Small Anim Pract       Date:  1990-05       Impact factor: 2.093

7.  Suppression of the immune system by oral glucocorticoid therapy in bronchial asthma.

Authors:  A G Oehling; C A Akdis; A Schapowal; K Blaser; M Schmitz; H U Simon
Journal:  Allergy       Date:  1997-02       Impact factor: 13.146

8.  Changes in leukocyte subpopulations following total hip replacement surgery. Effects of high doses of corticosteroids.

Authors:  H E Høgevold; T Lyberg; O Reikerås
Journal:  Scand J Clin Lab Invest       Date:  1991-09       Impact factor: 1.713

9.  Effect of corticosteroid therapy on the phagocytosis of antibody-coated platelets by human leukocytes.

Authors:  R I Handin; T P Stossel
Journal:  Blood       Date:  1978-05       Impact factor: 22.113

10.  Enhancement of human monocyte beta-glucan receptors by glucocorticoids.

Authors:  J Kay; J K Czop
Journal:  Immunology       Date:  1994-01       Impact factor: 7.397

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  2 in total

1.  The PHA test as an indicator of phagocytic activity in a passerine bird.

Authors:  Concepción Salaberria; Jaime Muriel; María de Luna; Diego Gil; Marisa Puerta
Journal:  PLoS One       Date:  2013-12-31       Impact factor: 3.240

2.  Hyposialylated α1-acid glycoprotein inhibits phagocytosis of feline neutrophils.

Authors:  G Rossi; L Capitani; F Ceciliani; L Restelli; S Paltrinieri
Journal:  Res Vet Sci       Date:  2013-05-31       Impact factor: 2.534

  2 in total

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