Literature DB >> 14672360

Racial differences in bone mineral density in older men.

Asha George1, J Kathleen Tracy, Walter A Meyer, Raymond H Flores, P David Wilson, Marc C Hochberg.   

Abstract

UNLABELLED: Studies have examined factors related to BMD in older white, but not black, men. We measured BMD in older white and black men and examined factors related to racial differences in BMD. Black men had significantly higher adjusted BMD at all sites. These results may explain, in part, the lower incidence of fractures in older black men.
INTRODUCTION: Several studies have examined factors associated with bone mineral density (BMD)in older men. None, however, have had sufficient numbers of black men to allow for meaningful comparisons by race.
MATERIALS AND METHODS: A total of 503 white and 191 black men aged 65 and older(75.1 +/- 5.8 and 72.2 +/- 5.7 years, respectively) were recruited from the Baltimore metropolitan area. All men completed a battery of self-administered questionnaires, underwent a standardized examination, and had BMD measured at the femoral neck, lumbar spine, and total body. Data were analyzed using multiple variable linear regression models, adjusted for potential confounding variables; two-way interactions with main effects were included in models where appropriate.
RESULTS: Black men had significantly higher adjusted BMD at the femoral neck (difference 0.09 [95% CI: 0.07, 0.12] mg/cm2), lumbar spine (0.07 [0.04, 0.10] mg/cm2), and total body (0.06 [0.03, 0.08] mg/cm2) than white men.
CONCLUSIONS: Older black men have significantly higher BMD than older white men, even after adjustment for factors associated with BMD. These differences, especially at the femoral neck, may explain the reduced incidence of hip fracture in black compared with white men.

Entities:  

Mesh:

Year:  2003        PMID: 14672360     DOI: 10.1359/jbmr.2003.18.12.2238

Source DB:  PubMed          Journal:  J Bone Miner Res        ISSN: 0884-0431            Impact factor:   6.741


  36 in total

1.  Generalized bone loss as a predictor of three-year radiographic damage in African American patients with recent-onset rheumatoid arthritis.

Authors:  Jie Zhang; David T Redden; Gerald McGwin; Leigh F Callahan; Edwin A Smith; Graciela S Alarcón; Larry W Moreland; Désirée M van der Heijde; Elizabeth E Brown; Donna K Arnett; Ted R Mikuls; S Louis Bridges
Journal:  Arthritis Rheum       Date:  2010-08

2.  Competing Risks of Fracture and Death in Older Adults with Chronic Kidney Disease.

Authors:  Rasheeda K Hall; Richard Sloane; Carl Pieper; Courtney Van Houtven; Joanne LaFleur; Robert Adler; Cathleen Colón-Emeric
Journal:  J Am Geriatr Soc       Date:  2018-01-10       Impact factor: 5.562

3.  Age trends in proximal femur geometry in men: variation by race and ethnicity.

Authors:  T G Travison; T J Beck; G R Esche; A B Araujo; J B McKinlay
Journal:  Osteoporos Int       Date:  2007-11-24       Impact factor: 4.507

4.  The relationship between body composition and bone mineral content: threshold effects in a racially and ethnically diverse group of men.

Authors:  T G Travison; A B Araujo; G R Esche; J B McKinlay
Journal:  Osteoporos Int       Date:  2007-07-28       Impact factor: 4.507

5.  Correlates of trabecular and cortical volumetric BMD in men of African ancestry.

Authors:  Yahtyng Sheu; Jane A Cauley; Clareann H Bunker; Victor W Wheeler; Alan L Patrick; Christopher L Gordon; Candace M Kammerer; Joseph M Zmuda
Journal:  J Bone Miner Res       Date:  2009-12       Impact factor: 6.741

6.  A single nucleotide polymorphism in osteonectin 3' untranslated region regulates bone volume and is targeted by miR-433.

Authors:  Neha S Dole; Kristina Kapinas; Catherine B Kessler; Siu-Pok Yee; Douglas J Adams; Renata C Pereira; Anne M Delany
Journal:  J Bone Miner Res       Date:  2015-04       Impact factor: 6.741

7.  Lumbar spine bone mineral density in US adults: demographic patterns and relationship with femur neck skeletal status.

Authors:  A C Looker; L J Melton; L G Borrud; J A Shepherd
Journal:  Osteoporos Int       Date:  2011-07-01       Impact factor: 4.507

8.  Racial differences in bone mineral density and fractures in men receiving androgen deprivation therapy for prostate cancer.

Authors:  Alicia K Morgans; Michael L Hancock; K Gary Barnette; Mitchell S Steiner; Ronald A Morton; Matthew R Smith
Journal:  J Urol       Date:  2012-01-15       Impact factor: 7.450

9.  Bone Mineral Density as a Predictor of Atherosclerosis and Arterial Wall Stiffness in Obese African-American Women.

Authors:  Samy I McFarlane; Ghazanfar Qureshi; Gagandeep Singh; Kinda Venner-Jones; Louis Salciccioli; Jason Lazar
Journal:  Cardiorenal Med       Date:  2012-11-24       Impact factor: 2.041

10.  Bone density testing among prostate cancer survivors treated with androgen-deprivation therapy.

Authors:  Alicia K Morgans; Matthew R Smith; A James O'Malley; Nancy L Keating
Journal:  Cancer       Date:  2012-10-12       Impact factor: 6.860

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.