Literature DB >> 14670878

Gulf war illness--better, worse, or just the same? A cohort study.

Matthew Hotopf1, Anthony S David, Lisa Hull, Vasilis Nikalaou, Catherine Unwin, Simon Wessely.   

Abstract

OBJECTIVES: Firstly, to describe changes in the health of Gulf war veterans studied in a previous occupational cohort study and to compare outcome with comparable non-deployed military personnel. Secondly, to determine whether differences in prevalence between Gulf veterans and controls at follow up can be explained by greater persistence or greater incidence of disorders.
DESIGN: Occupational cohort study in the form of a postal survey. PARTICIPANTS: Military personnel who served in the 1991 Persian Gulf war; personnel who served on peacekeeping duties to Bosnia; military personnel who were deployed elsewhere ("Era" controls). All participants had responded to a previous survey.
SETTING: United Kingdom. MAIN OUTCOME MEASURES: Self reported fatigue measured on the Chalder fatigue scale; psychological distress measured on the general health questionnaire, physical functioning and health perception on the SF-36; and a count of physical symptoms.
RESULTS: Gulf war veterans experienced a modest reduction in prevalence of fatigue (48.8% at stage 1, 43.4% at stage 2) and psychological distress (40.0% stage 1, 37.1% stage 2) but a slight worsening of physical functioning on the SF-36 (90.3 stage 1, 88.7 stage 2). Compared with the other cohorts Gulf veterans continued to experience poorer health on all outcomes, although physical functioning also declined in Bosnia veterans. Era controls showed both lower incidence of fatigue than Gulf veterans, and both comparison groups showed less persistence of fatigue compared with Gulf veterans.
CONCLUSIONS: Gulf war veterans remain a group with many symptoms of ill health. The excess of illness at follow up is explained by both higher incidence and greater persistence of symptoms.

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Year:  2003        PMID: 14670878      PMCID: PMC292982          DOI: 10.1136/bmj.327.7428.1370

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  15 in total

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2.  Self-reported symptoms and medical conditions among 11,868 Gulf War-era veterans: the Seabee Health Study.

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3.  Increased postwar symptoms and psychological morbidity among U.S. Navy Gulf War veterans.

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4.  Chronic multisymptom illness affecting Air Force veterans of the Gulf War.

Authors:  K Fukuda; R Nisenbaum; G Stewart; W W Thompson; L Robin; R M Washko; D L Noah; D H Barrett; B Randall; B L Herwaldt; A C Mawle; W C Reeves
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5.  Health and exposures of United Kingdom Gulf war veterans. Part I: The pattern and extent of ill health.

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7.  Neurophysiologic analysis of neuromuscular symptoms in UK Gulf War veterans: a controlled study.

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8.  Health status of Persian Gulf War veterans: self-reported symptoms, environmental exposures and the effect of stress.

Authors:  S P Proctor; T Heeren; R F White; J Wolfe; M S Borgos; J D Davis; L Pepper; R Clapp; P B Sutker; J J Vasterling; D Ozonoff
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10.  Health of UK servicemen who served in Persian Gulf War.

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  18 in total

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5.  Health effects associated with geographical area of residence during the 1991 Gulf War: a comparative health study of Iraqi soldiers and civilians.

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7.  Getting a peace of the action: measures of post traumatic stress in UK military peacekeepers.

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8.  Acetylcholinesterase inhibitors and Gulf War illnesses.

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Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-10       Impact factor: 11.205

9.  Gulf War syndrome: an emerging threat or a piece of history?

Authors:  N Greenberg; S Wessely
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10.  Persistence of symptoms in veterans of the First Gulf War: 5-year follow-up.

Authors:  Gozde Ozakinci; William K Hallman; Howard M Kipen
Journal:  Environ Health Perspect       Date:  2006-10       Impact factor: 9.031

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